v3.6.0.2
Document and Entity Information - USD ($)
$ in Millions
12 Months Ended
Dec. 31, 2016
Feb. 28, 2017
Jun. 30, 2016
Document And Entity Information [Abstract]      
Document Type 10-K    
Amendment Flag false    
Document Period End Date Dec. 31, 2016    
Document Fiscal Year Focus 2016    
Document Fiscal Period Focus FY    
Trading Symbol CTMX    
Entity Registrant Name CytomX Therapeutics, Inc.    
Entity Central Index Key 0001501989    
Current Fiscal Year End Date --12-31    
Entity Well-known Seasoned Issuer No    
Entity Voluntary Filers No    
Entity Current Reporting Status Yes    
Entity Filer Category Accelerated Filer    
Entity Public Float     $ 197.3
Entity Common Stock, Shares Outstanding   36,518,184