Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Expected Volatility Rate, Maximum
Expected volatility, maximum
Impairment, Long-Lived Asset, Held-for-Use, Total
Impairment, Long-Lived Asset, Held-for-Use
Impairment of long-lived assets
Income (Loss) from Continuing Operations, Per Basic and Diluted Share
Net loss per share, basic and diluted
Lessee, Operating Lease, Description
Lease term description
Accelerated recognition of deferred revenue.
Accelerated Recognition Of Deferred Revenue [Member]
Accelerated Recognition of Deferred Revenue
Share-based Compensation Arrangement by Share-based Payment Award, Award Vesting Period
Options granted generally vest period
Contingent Consideration by Type [Axis]
Contingent Consideration by Type
Segment Reporting, Policy [Policy Text Block]
Segments
Litigation Case [Axis]
Litigation Case
Share-based Compensation Arrangement by Share-based Payment Award, Award Vesting Rights
Vesting rights, description
Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Outstanding, Weighted Average Remaining Contractual Terms
Balances, end of the period
Tax Cuts and Jobs Act, Reclassification from AOCI to Retained Earnings, Tax Effect
Impact of adoption of new accounting pronouncement
Operating Loss Carryforwards, Total
Operating Loss Carryforwards
Net operating loss carryforwards
Forecast [Member]
Forecast
Tax Credit Carryforward Expiration Year
Tax credit carryforward, expiration
Tax credit carryforward expiration year.
Auditor Location
Auditor Location
Share based compensation arrangement by share based payment award number of shares available for grant grants in period.
Share Based Compensation Arrangement By Share Based Payment Award Number Of Shares Available For Grant Grants In Period
Options granted
Operating Expenses [Abstract]
Operating expenses:
Finite-Lived Intangible Assets by Major Class [Axis]
Finite-Lived Intangible Assets by Major Class
Asset Class [Domain]
Asset Class
Operating Income (Loss)
Loss from operations
Goodwill.
Goodwill [Abstract]
Goodwill
Cash, cash equivalents and short term investments, allowance for credit loss.
Cash Cash Equivalents And Short Term Investments Allowance For Credit Loss
Allowance for Credit Losses
Pfizer Inc.
Pfizer Inc [Member]
Pfizer Inc
Pfizer
Entity Emerging Growth Company
Entity Emerging Growth Company
Income Tax Disclosure [Abstract]
Increase (Decrease) in Prepaid Expense and Other Assets
Prepaid expenses and other current assets
Increase (Decrease) in Prepaid Expense and Other Assets, Total
Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Forfeitures, Weighted Average Grant Date Fair Value
RSU's Cancelled
Shares available for future grants
Share-based Compensation Arrangement by Share-based Payment Award, Number of Shares Available for Grant
Balances, beginning of the period
Balances, end of the period
Marketable Securities, Policy [Policy Text Block]
Investments
Payments to Acquire Property, Plant, and Equipment
Purchases of property and equipment
Payments to Acquire Property, Plant, and Equipment, Total
Cash, cash equivalents and short term investments, accumulated gross unrealized gain before tax.
Cash Cash Equivalents And Short Term Investments Accumulated Gross Unrealized Gain Before Tax
Gross Unrealized Holding Gains
Geographical [Axis]
Geographical
Common Stock, Value, Issued
Common Stock, Value, Issued, Total
Common Stock, Value, Issued, Beginning Balance
Common Stock, Value, Issued, Ending Balance
Common stock, $0.00001 par value; 150,000,000 and 150,000,000 shares authorized at December 31, 2021 and 2020, respectively; 48,251,819 and 48,251,819 shares issued and outstanding at December 31, 2021 and 2020, respectively
Entity Address, State or Province
Entity Address, State or Province
Liabilities
Total liabilities
Disaggregation of Revenue [Table Text Block]
Schedule of Revenue by Collaboration Partners
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Sublicense fees.
Sublicense Fees
Sublicense fees
Share-based Payment Arrangement, Expensed and Capitalized, Amount [Table]
Goodwill
Goodwill
Goodwill, Total
Goodwill, Beginning Balance
Goodwill, Ending Balance
Finite-lived Intangible Assets Acquired
Acquired, technology know-how
Milestone payment received.
Milestone Payment Received
Milestone payments received
Amount of increase decrease in unrecognized tax benefits resulting from tax positions taken in prior period tax returns.
Unrecognized Tax Benefits Increase Decrease Resulting From Prior Period Tax Positions
Adjustment based on tax positions related to prior years
Class of Stock [Domain]
Class of Stock
Schedule of Stock by Class [Table Text Block]
Schedule Reserved Shares of Common Stock Issuance on Converted Basis
Royalty obligations future minimum payments due.
Royalty Obligations Future Minimum Payments Due
Annual minimum royalty obligations
Period of nomination of additional target.
Period Of Nomination Of Additional Target
Period of nomination of additional target from effective date
Regents of the university of California.
Regents Of The University Of California [Member]
UC Regents
Share based compensation arrangement by share based payment award other than options exercisable number.
Share Based Compensation Arrangement by Share Based Payment Award Other than Options Exercisable Number
Exercisable, end of the period
Weighted Average Number of Shares Outstanding, Basic and Diluted
Shares used to compute net loss per share, basic and diluted
Profit share upon exercise of co-development option.
Profit Share Upon Exercise Of Co Development Option
Percentage share of profit and losses
Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding [Roll Forward]
Number of Options
Property, Plant and Equipment, Estimated Useful Lives
Estimated useful life of leasehold improvements, description
Deferred Tax Liabilities, Property, Plant and Equipment
Fixed assets
Defined Contribution Plan, Employer Discretionary Contribution Amount
Company contributions to defined contribution plan
General and Administrative Expense [Member]
General and administrative
Annual license maintenance fees
Annual License Maintenance Fees
Annual license maintenance fees
Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercisable, Weighted Average Remaining Contractual Term
Options Exercisable, end of the period
Ending Exercisable - December 31, 2021
Share based compensation arrangement by share based payment award options aggregate intrinsic value.
Share Based Compensation Arrangement By Share Based Payment Award Options Aggregate Intrinsic Value [Abstract]
Aggregate Intrinsic Value
Accounts Receivable, after Allowance for Credit Loss, Current
Accounts receivable
Accounts Receivable, after Allowance for Credit Loss, Current, Total
Debt Securities, Available-for-sale, Current
Short-term investments
Debt Securities, Available-for-sale, Current, Total
Fair Value, Recurring and Nonrecurring [Table]
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Table]
Contract with Customer, Liability, Revenue Recognized
Deductions
Deductions to deferred revenue recognized during the period
City Area Code
City Area Code
Schedule of Share-based Payment Award, Stock Options, Valuation Assumptions [Table Text Block]
Schedule of Estimated Fair Value of Employee Stock Options and ESPP Using Black-Scholes Valuation Model
Deferred Tax Assets, Gross
Total gross deferred income tax assets
Deferred Tax Assets, Net of Valuation Allowance
Deferred tax assets, net of valuation allowance
License agreement.
License Agreement Disclosure [Text Block]
License Agreement
Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Nonvested, Weighted Average Grant Date Fair Value [Abstract]
Weighted Average Grant Date Fair Value
Disclosure Text Block [Abstract]
Change in Accounting Principle, Accounting Standards Update, Adopted [true false]
Change in accounting principle, accounting standards update, adopted [true false]
Share-based Compensation Arrangements by Share-based Payment Award, Options, Forfeitures in Period, Weighted Average Exercise Price
Options cancelled
Supplemental information related to leases.
Supplemental Information Related To Leases Table [Text Block]
Summary of Supplemental Information Related to Leases
Goodwill and Intangible Assets Disclosure [Abstract]
Contract with Customer, Liability
Deferred revenue
Estimated total fair value consideration recorded as deferred revenue
Contract with Customer, Liability, Total
Balance at 12/31/2020
Balance at 12/31/2021
Commitments and Contingencies
Commitments and contingencies (Note 11)
Second twelve months of lease term.
Second Twelve Months Of Lease Term [Member]
Second twelve months of lease term
Acquired Finite-lived Intangible Assets, Weighted Average Useful Life
Average estimated lives of patents
Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block]
Summary of Potentially Dilutive Securities Excluded from Computation of Diluted Net Loss Per Share
Finite-Lived Intangible Assets, Net
Intangible assets, net
Finite-Lived Intangible Assets, Net, Beginning Balance
Finite-Lived Intangible Assets, Net, Ending Balance
Estimated research service termination month and year.
Estimated Research Service Termination Month And Year
Estimated research service termination month & year
Stock Issued During Period, Shares, New Issues
Issuance of common stock in follow-on offering, net of issuance costs, shares
Issuance of common stock to UCSB and Open Market Sale Agreement, net of issuance cost, shares
Aggregate Fair Value
Debt Securities, Available-for-sale
Debt Securities, Available-for-sale, Total
Scenario [Axis]
Scenario
Basis of Accounting, Policy [Policy Text Block]
Basis of Presentation
Stock Issued During Period, Shares, Employee Stock Purchase Plans
Issuance of common stock under the Employee Stock Purchase Plan, shares
Number of shares issued during period
Change in Accounting Principle, Accounting Standards Update, Immaterial Effect [true false]
Change in accounting principle, accounting standards update, immaterial effect [true false]
Amgen Inc.
Amgen Inc [Member]
Amgen Inc
Amgen
Schedule of Share-based Compensation Arrangements by Share-based Payment Award [Table]
Schedule Of Share Based Compensation Arrangements By Share Based Payment Award [Table]
US Treasury and Government Short-term Debt Securities [Member]
U.S. Government bonds - Short Term
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items]
Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Additional Disclosures [Abstract]
Weighted Average Remaining Contractual Life (years)
Net Cash Provided by (Used in) Investing Activities
Net cash provided by (used in) investing activities
Capital Expenditures Incurred but Not yet Paid
Purchases of property and equipment in accounts payable and accrued liabilities
Tax Credit Carryforward [Axis]
Tax Credit Carryforward
Share-based Compensation Arrangement by Share-based Payment Award, Percentage of Outstanding Stock Maximum
Increase in number of shares available for issuance, as proportion of issued and outstanding shares of common stock, percentage
Tax Credit Carryforward, Name [Domain]
Tax Credit Carryforward, Name
Employee-related Liabilities, Current
Payroll and related expenses
Employee-related Liabilities, Current, Total
General and Administrative Expense
General and administrative
General and Administrative Expense, Total
Property, Plant and Equipment, Net
Property and equipment, net
Property and equipment, net
Property, Plant and Equipment, Net, Beginning Balance
Property, Plant and Equipment, Net, Ending Balance
Contract with Customer, Liability, Current
Deferred revenues, current portion
Common Stock, Shares, Issued
Common stock, shares issued
Common Stock, Shares, Issued, Total
Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Forfeited in Period
RSU's Cancelled
Statement of Comprehensive Income [Abstract]
Deferred Tax Liabilities, Gross
Deferred tax liabilities
Deferred Tax Liabilities, Gross, Total
Share based compensation arrangement by share based payment award options authorized.
Share Based Compensation Arrangement By Share Based Payment Award Options Authorized
Options authorized
Debt Securities, Available-for-sale, Amortized Cost
Short-term Investments, Amortized Cost
Short-term Investments, Amortized Cost
Operating Lease, Right-of-Use Asset
Operating lease right-of-use asset
Right-of-use asset
Security Exchange Name
Security Exchange Name
Statistical Measurement [Domain]
Statistical Measurement
Furniture and Fixtures [Member]
Furniture and fixtures
Common stock shares issuable under agreement.
Common Stock Shares Issuable Under Agreement
Common stock, shares issuable under agreement
Accounting Standards Update 2019-12 [Member]
ASU 2019-12
Finite-Lived Intangible Assets, Gross
Intangible assets, gross
Finite-Lived Intangible Assets, Gross, Total
Finite-Lived Intangible Assets, Net [Abstract]
Intangible assets
Document Period End Date
Document Period End Date
AbbVie Ireland Unlimited Company.
Abb Vie Ireland Unlimited Company [Member]
AbbVie Ireland Unlimited Company
AbbVie
Restricted cash - non-current assets
Restricted Cash, Noncurrent
Income Statement Location [Axis]
Income Statement Location
Accrued Liabilities, Current
Accrued liabilities
Total
Estimated fair value of products.
Estimated Fair Value Of Products
Estimated fair value of products
Loss Contingencies [Table]
Loss Contingencies [Table]
Common Stock, Shares Authorized
Common stock, shares authorized
Use of Estimates, Policy [Policy Text Block]
Use of Estimates
Deferred Tax Assets, Deferred Income
Deferred revenue
U.S. Government bonds
US Treasury and Government [Member]
First target under discovery agreement.
First Target Under Discovery Agreement [Member]
First Target under Discovery Agreement
First Target under Discovery Agreement
Operating Lease, Liability, Current
Operating lease liabilities - short term
Current operating lease liabilities
Amortization of premium (accretion of discounts) on investments
Accretion (Amortization) of Discounts and Premiums, Investments
Contract with Customer, Asset, after Allowance for Credit Loss
Amount due from agreement
Contract with Customer, Asset, after Allowance for Credit Loss, Total
Amount due from customer
Derivative Contract [Domain]
Derivative Contract
Supplemental Cash Flow Information [Abstract]
Supplemental disclosures of cash flow information:
Lease Agreements [Member]
New Lease Agreement
Class of Stock [Axis]
Class of Stock
Adjustments to Reconcile Net Income (Loss) to Cash Provided by (Used in) Operating Activities [Abstract]
Adjustments to reconcile net loss to net cash (used in) provided by operating activities:
Common stock.
Common Stock [Text Block]
Common Stock
Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount
Anti-dilutive securities excluded from computation of diluted net loss per share
Contingent payments payable upon achieving development regulatory and commercial milestones.
Contingent Payments Payable Upon Achieving Development Regulatory And Commercial Milestones
Contingent payments payable
Cumulative Effect, Period of Adoption [Axis]
Cumulative Effect, Period of Adoption
Vesting [Axis]
Vesting
Deferred Tax Assets, Tax Deferred Expense, Compensation and Benefits, Share-based Compensation Cost
Stock-based compensation
Timing of Transfer of Good or Service [Axis]
Timing of Transfer of Good or Service
Accounts Payable and Accrued Liabilities Disclosure [Text Block]
Accrued Liabilities
Schedule of cash, cash equivalents, and restricted cash.
Schedule Of Cash Cash Equivalents And Restricted Cash Table [Text Block]
Schedule of Cash, Cash Equivalents, and Restricted Cash
Effective Income Tax Rate Reconciliation, Percent
Total
Schedule of Fair Value, Assets and Liabilities Measured on Recurring Basis [Table Text Block]
Schedule of Investments Subject to Fair Value Measurements on a Recurring Basis
Entity Address, Address Line Two
Entity Address, Address Line Two
Machinery and Equipment [Member]
Machinery and equipment
Current Fiscal Year End Date
Current Fiscal Year End Date
Share based compensation arrangement by share based payment award, number of shares available for grant.
Share Based Compensation Arrangement By Share Based Payment Award Number Of Shares Available For Grant [Abstract]
Options Available for Grant
Revenue, Remaining Performance Obligation, Expected Timing of Satisfaction, Period
Revenue recognition upon performance obligation, service period
Increase (Decrease) in Other Operating Assets
Other assets
Increase (Decrease) in Other Operating Assets, Total
Deferred Tax Assets, Other
Other
Counterparty Name [Axis]
Counterparty Name
Assets [Abstract]
Assets
Impairment Effects on Earnings Per Share [Table]
Unrecognized Tax Benefits that Would Impact Effective Tax Rate
Unrecognized tax benefits would affect company's effective tax rate
Amgen other products.
Amgen Other Products [Member]
Amgen Other Products
Money market funds included in restricted cash.
Money Market Funds Included In Restricted Cash [Member]
Restricted cash (money market funds)
First year of lease term.
First Year Of Lease Term [Member]
First year of lease term
Lessee, Operating Lease, Liability, to be Paid, Year One
2022
Accounts Payable, Current
Accounts payable
Accounts Payable, Current, Total
Improvement allowance from recoverable rent.
Improvement Allowance From Recoverable Rent
Improvement allowance from recoverable rent
Common Stock, Par or Stated Value Per Share
Common stock, par value
Revenue from Contract with Customer [Policy Text Block]
Contract Balances
Patent infringement lawsuit.
Patent Infringement Lawsuit [Member]
Patent Infringement Lawsuit
Schedule of Components of Benefit from Income Taxes
Schedule of Components of Income Tax Expense (Benefit) [Table Text Block]
Unrecognized Tax Benefits, Increase Resulting from Current Period Tax Positions
Additions based on tax positions related to current year
State and Local Jurisdiction [Member]
State
Options, RSUs and ESPP to purchase common stock
Options RSUs and ESPP to Purchase Common Stock Member
Options RSUs and ESPP to Purchase Common Stock Member
Share based compensation arrangement by share based payment award number of shares available for grant authorized.
Share Based Compensation Arrangement By Share Based Payment Award Number Of Shares Available For Grant Authorized
Options authorized
Second Target Under Discovery Agreement [Member]
Second Target under Discovery Agreement
Second target under discovery agreement.
Second Target under Discovery Agreement
Current Income Tax Expense (Benefit)
Total current
Number of targets.
Number Of Targets
Number of targets
Research and Development Expense, Policy [Policy Text Block]
Research and Development Expenses
Other Comprehensive Income (Loss), Tax [Abstract]
Other comprehensive income (loss):
Operating Leased Assets [Line Items]
Operating Leased Assets [Line Items]
Percentage of sales commission and issuance cost.
Percentage Of Sales Commission And Issuance Cost
Percentage of sales commission and issuance cost
Net operating loss carryback.
Net Operating Loss Carryback Period
Net operating loss carryback
Income (Loss) from Continuing Operations before Income Taxes, Noncontrolling Interest
Loss before income taxes
Document Type
Document Type
Vesting [Domain]
Vesting
Share based compensation arrangement by share based payment award number of shares available for grant exercises in period.
Share Based Compensation Arrangement By Share Based Payment Award Number Of Shares Available For Grant Exercises In Period
Options exercised
Domestic Tax Authority [Member]
Federal
Effective Income Tax Rate Reconciliation, Percent [Abstract]
Share based compensation arrangement by share based payment award equity instruments other than options vested and expected to vest weighted average grant date fair value.
Share Based Compensation Arrangement by Share Based Payment Award Equity Instruments Other Than Options Vested and Expected to Vest Weighted Average Grant Date Fair Value
Vested and Expected to Vest, end of the period
Preferred Stock, Value, Issued
Preferred Stock, Value, Issued, Total
Preferred Stock, Value, Issued, Beginning Balance
Preferred Stock, Value, Issued, Ending Balance
Convertible preferred stock, $0.00001 par value; 10,000,000 shares authorized and no shares issued and outstanding at December 31, 2021 and 2020
Operating Lease, Liability, Noncurrent
Operating lease liabilities - long term
Non-current operating lease liabilities
Schedule of Accrued Liabilities [Table Text Block]
Schedule of Accrued Liabilities
Assets, Current
Total current assets
Milestone payments receivable.
Milestone Payments Receivable
Milestone payment received
Share-based Payment Arrangement [Policy Text Block]
Stock-Based Compensation
Research and Development Arrangement, Contract to Perform for Others, Description and Terms
Research terms
Noncash lease expense.
Noncash Lease Expense
Non-cash lease expense
Non-cash lease expense
Share-based Payment Arrangement, Option [Member]
Employee Stock Option
Research and Development Arrangement, Contract to Perform for Others, Type [Axis]
Research and Development Arrangement, Contract to Perform for Others, Type
Deferred Federal Income Tax Expense (Benefit)
Federal
Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Weighted Average Remaining Contractual Term
Balances, end of the period
Income tax expense (benefit)
Benefit from income taxes
Benefit from income taxes
Income Tax Expense (Benefit)
Income tax expense (benefit)
Cash payment to execute the agreement.
Cash Payment To Execute Agreement
Upfront cash payment
Area of Land
Area of rentable office and laboratory space
Leases [Abstract]
University of California, Santa Barbara.
University Of California Santa Barbara [Member]
UCSB
Loss Contingencies [Line Items]
Loss Contingencies [Line Items]
Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Nonvested, Number
Balances, beginning of the period
Balances, end of the period
Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested and Expected to Vest, Outstanding, Aggregate Intrinsic Value
Options vested and expected to vest—December 31, 2020
Vested and Expected to Vest - December 31, 2021
Deferred Tax Assets, Operating Loss Carryforwards
Net operating loss carryforwards
Deferred Tax Assets, Operating Loss Carryforwards, Total
Operating loss carryforwards expiration year.
Operating Loss Carryforwards Expiration Year
Operating loss carryforwards expiration year
Common Stock, Shares, Outstanding
Common stock, shares outstanding
Common Stock, Shares, Outstanding, Beginning Balance
Common Stock, Shares, Outstanding, Ending Balance
Current State and Local Tax Expense (Benefit)
State
Plan Name [Axis]
Plan Name
Options and awards issued and outstanding
Stock options issued and outstanding.
Stock Options Issued And Outstanding
Finite-Lived Intangible Assets [Line Items]
Finite Lived Intangible Assets [Line Items]
Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment
Less: accumulated depreciation and amortization
Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment, Total
Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment, Beginning Balance
Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment, Ending Balance
Share-based Compensation Arrangement by Share-based Payment Award, Options, Forfeitures in Period
Options cancelled
Collaborative Arrangement and Arrangement Other than Collaborative [Table]
Schedule Of Collaborative Arrangements And Noncollaborative Arrangement Transactions [Table]
Revenue [Policy Text Block]
Revenue Recognition
Deferred Income Tax Expense (Benefit)
Total deferred
Operating Expenses
Total operating expenses
License payment percentage equivalence to upfront and milestone proceeds.
License Payment Percentage Equivalence To Upfront And Milestone Proceeds
Sublicense payment percentage
Debt Securities, Available-for-sale, Accumulated Gross Unrealized Loss, before Tax
Short-term Investments, Gross Unrealized Holding Losses
Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Weighted Average Exercise Price
Balances, end of the period
Balances, beginning of the period
Net Cash Provided by (Used in) Operating Activities [Abstract]
Cash flows from operating activities:
Deferred Income Tax Expense (Benefit), Continuing Operations [Abstract]
Deferred:
Accounting Standards Update [Extensible Enumeration]
Accounting Standards Update [Extensible List]
Income Tax Contingency [Line Items]
Income Tax Contingency [Line Items]
Lessee, Operating Lease, Liability, Maturity [Table Text Block]
Schedule of Maturity of Operating Lease Liabilities
Weighted average discount rate.
Weighted Average Discount Rate [Abstract]
Weighted-average discount rate
Debt Securities, Available-for-sale, Accumulated Gross Unrealized Gain, before Tax
Short-term Investments, Gross Unrealized Holding Gains
Jefferies.
Jefferies [Member]
Jefferies LLC
Earnings Per Share [Abstract]
Number of business activities.
Number Of Business Activities
Number of business activities
Lessee, Operating Lease, Liability, to be Paid, Year Two
2023
Net Income (Loss) Attributable to Parent
Net loss
Net loss
Concentration Risk [Line Items]
Concentration Risk [Line Items]
Schedule of Effective Income Tax Rate Reconciliation [Table Text Block]
Schedule of Effective Tax Rate Reconciliation
Concentration Risk, Credit Risk, Policy [Policy Text Block]
Concentration of Credit Risk and Other Risks and Uncertainties
Operating Lease, Weighted Average Discount Rate, Percent
Operating lease
Research and Development Expense [Member]
Research and development
Document Fiscal Period Focus
Document Fiscal Period Focus
Accounting Policies [Abstract]
Accumulated Other Comprehensive Income (Loss), Net of Tax
Accumulated other comprehensive income (loss)
Accumulated Other Comprehensive Income (Loss), Net of Tax, Total
Sublicense and maintenance fees.
Sublicense And Maintenance Fees [Member]
Sublicense and Maintenance Fees
Entity Address, Address Line One
Entity Address, Address Line One
Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercises in Period, Intrinsic Value
Options exercised
Aggregate intrinsic value of stock options exercised
Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Number
Balances, end of the period
Balances, beginning of the period
AbbVie .
Abb Vie [Member]
AbbVie
Estimated sublicense fees.
Estimated Sublicense Fees
Estimated sublicense fees
Bristol-Myers Squibb Company.
Bristol Myers Squibb Company [Member]
Bristol Myers Squibb Company
Bristol Myers Squibb
Liabilities, Current
Total current liabilities
Finite-Lived Intangible Assets, Accumulated Amortization
Less accumulated amortization
Net Income (Loss), Including Portion Attributable to Noncontrolling Interest
Net loss
Net Income (Loss), Including Portion Attributable to Noncontrolling Interest, Total
Entity Address, Postal Zip Code
Entity Address, Postal Zip Code
Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Aggregate Intrinsic Value [Abstract]
Aggregate Intrinsic Value
Collaboration and license agreement.
Collaboration And License Agreement [Member]
Collaboration and License Agreement
Contingent payments receivable upon achieving development, regulatory and commercial milestones.
Contingent Payments Receivable Upon Achieving Development Regulatory And Commercial Milestones
Contingent payments receivable upon achieving development, regulatory and commercial milestones
Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Risk Free Interest Rate, Maximum
Risk-free interest rate, maximum
Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Intrinsic Value
Balances at December 31, 2020
Balances at December 31, 2021
Lessee, Operating Lease, Liability, to be Paid
Total lease payments
Product and Service [Domain]
Product and Service
Maturities of investments
Proceeds from Sale of Debt Securities, Available-for-sale
Revenues
Revenue
Revenues, Total
Convertible Preferred Stock [Member]
Convertible Preferred Stock
Collaborative Arrangement and Arrangement Other than Collaborative [Domain]
Collaborative Arrangement and Arrangement Other than Collaborative
Schedule of Research and Development Arrangement, Contract to Perform for Others [Table]
Schedule Of Research And Development Arrangement Contract To Perform For Others [Table]
Percentage of taxable income from net operating losses for suspension of annual deduction limitation.
Percentage Of Taxable Income From Net Operating Losses For Suspension Of Annual Deduction Limitation
Percentage of taxable income from net operating losses for suspension of annual deduction limitation
Net Cash Provided by (Used in) Operating Activities
Net cash provided by (used in) operating activities
Effective income tax rate reconciliation return to provision adjustments.
Effective Income Tax Rate Reconciliation Return To Provision Adjustments
Return to provision adjustment
Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents, Including Disposal Group and Discontinued Operations
Cash, cash equivalents and restricted cash, end of year
Cash, cash equivalents and restricted cash, beginning of year
Cash, cash equivalents, and restricted cash
Equity Components [Axis]
Equity Components
Assets, Current [Abstract]
Current assets:
Restricted Cash and Cash Equivalents, Current
Restricted cash
Restricted Cash and Cash Equivalents, Current, Total
Entity Registrant Name
Entity Registrant Name
Depreciation and amortization excluding amortization of intangible assets.
Depreciation And Amortization Excluding Amortization Of Intangible Assets
Depreciation and amortization
Achieving additional targets.
Achieving Additional Targets [Member]
Each Of Two Additional Targets
Entity Interactive Data Current
Entity Interactive Data Current
Research and collaboration agreements.
Research And Collaboration Agreements [Text Block]
Research and Collaboration Agreements
Entity Address, City or Town
Entity Address, City or Town
Number of additional collaboration target.
Number Of Additional Collaboration Target
Number of additional collaboration target
Customer [Axis]
Customer
Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Expected Volatility Rate, Minimum
Expected volatility, minimum
Additional contingent payments.
Additional Contingent Payments [Member]
Additional Contingent Payments
Current Federal, State and Local, Tax Expense (Benefit) [Abstract]
Current:
Effective Income Tax Rate Reconciliation, Tax Credit, Percent
Tax credits
Effective Income Tax Rate Reconciliation, Tax Credit, Percent, Total
Employee stock purchase plan.
Employee Stock Purchase Plan [Member]
Employee Stock Purchase Plan
Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Expected Term
Expected term (in years)
Trading Symbol
Trading Symbol
Percentage of sales commission.
Percentage Of Sales Commission
Percentage of sales commission
Net Cash Provided by (Used in) Investing Activities [Abstract]
Cash flows from investing activities:
Astellas Pharma Inc.
Astellas Pharma Inc [Member]
Astellas Pharma Inc.
Astellas
Lessee, Operating Lease, Liability, Undiscounted Excess Amount
Less imputed interest
Local Phone Number
Local Phone Number
Machinery and Equipment, Gross
Machinery and equipment
Machinery and Equipment, Gross, Total
Accounting Standards Update 2016-02 [Member]
ASC 842
Extension of research term for each collaboration target.
Extension Of Research Term For Each Collaboration Target
Extension of research term for each collaboration target
Number of collaboration target.
Number Of Collaboration Target
Number of collaboration target
Stockholders' Equity Attributable to Parent
Ending balance
Beginning balance
Total stockholders' equity
Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Weighted Average Exercise Price [Abstract]
Options Outstanding, Weighted-Average Exercise Price Per Share
Weighted - Average Purchase Price
Unrecognized Tax Benefits
Balance at end of the year
Balance at the beginning of the year
Unrecognized tax benefits
Discovery agreement.
Discovery Agreement [Member]
Discovery Agreement
Operating Lease, Payments
Operating cash flows from operating leases
Comprehensive Income, Policy [Policy Text Block]
Comprehensive Income (Loss)
Research and Development [Abstract]
Preferred Stock, Shares Issued
Convertible Preferred stock, shares issued
Preferred Stock, Shares Issued, Total
Share based compensation arrangement by share based payment award voting rights of common stock holding percentage.
Share Based Compensation Arrangement By Share Based Payment Award Voting Rights Of Common Stock Holding Percentage
Employees holding voting rights of all classes of stock, percentage
Milestone payment receivable.
Milestone Payment Receivable
Milestone payment receivable
Statistical Measurement [Axis]
Statistical Measurement
Period used to calculate weighted average price per share.
Period Used To Calculate Weighted Average Price Per Share
Period used to calculate weighted average price per share
Entity Small Business
Entity Small Business
Purchases of investments
Payments to Acquire Debt Securities, Available-for-sale
Preferred Stock, Shares Outstanding
Convertible Preferred stock, shares outstanding
Preferred Stock, Shares Outstanding, Beginning Balance
Preferred Stock, Shares Outstanding, Ending Balance
Organization, Consolidation and Presentation of Financial Statements [Abstract]
Lessee, Leases [Policy Text Block]
Leases
Share Price
Common stock, shares issuable under agreement, price per share
Fair Value Hierarchy and NAV [Domain]
Fair Value Hierarchy and NAV
APIC, Share-based Payment Arrangement, Increase for Cost Recognition
Stock-based compensation
APIC, Share-based Payment Arrangement, Increase for Cost Recognition, Total
Adopted accounting pronouncements.
Adopted Accounting Pronouncements [Text Block]
Adopted Accounting Pronouncements
Over-Allotment Option [Member]
Underwriters
Underwriters
Credit Facility [Axis]
Credit Facility
Schedule of Deferred Tax Assets and Liabilities [Table Text Block]
Schedule of Deferred Income Tax Assets and Liabilities
Deferred Tax Liabilities, Prepaid Expenses
Prepaid expenses
Impairment of Intangible Assets, Indefinite-lived (Excluding Goodwill)
Impairment of intangible assets
Accrued Liabilities, Current [Abstract]
Impairment or Disposal of Long-Lived Assets, Policy [Policy Text Block]
Impairment of Long-Lived Assets
Research Tax Credit Carryforward [Member]
Research and Development Tax Credits
Share-based Payment Arrangement, Tranche Two [Member]
Vesting per Month After First Anniversary
Accrued research and clinical current.
Accrued Research And Clinical Current
Research and clinical expenses
Property, Plant and Equipment, Useful Life
Estimated useful life of property and equipment
Accounting Standards Update 2014-09 [Member]
ASC 606
Additional Paid in Capital
Additional paid-in capital
Additional Paid in Capital, Ending Balance
Additional Paid in Capital, Total
Additional Paid in Capital, Beginning Balance
Reconciliation of Unrecognized Tax Benefits, Excluding Amounts Pertaining to Examined Tax Returns [Roll Forward]
Milestone payments received from revenue recognized during period.
Milestone Payments Received From Revenue Recognized During Period
Milestone payment received
Pre clinical candidate.
Pre Clinical Candidate [Member]
Pre Clinical Candidate
Share-based compensation arrangement by share-based payment award, number of shares available for future issuance under employee stock purchase plan.
Share Based Compensation Arrangement By Share Based Payment Award Number Of Shares Available For Future Issuance Under Employee Stock Purchase Plan
Shares available for future employee stock purchase plan
Number of oncology target.
Number Of Oncology Target
Number of oncology target
Share-based Compensation Arrangements by Share-based Payment Award, Options, Grants in Period, Weighted Average Exercise Price
Options granted
RSU's Awarded
Sale of Stock [Domain]
Sale of Stock
Equity [Abstract]
Share based compensation arrangement by share based payment award number of shares available for grant cancelled in period.
Share Based Compensation Arrangement By Share Based Payment Award Number Of Shares Available For Grant Cancelled In Period
Options cancelled
Revenue from Contract with Customer [Abstract]
Share based compensation arrangement by share based payment award other than options vested and expected to vest outstanding weighted average remaining contractual term.
Share Based Compensation Arrangement by Share Based Payment Award Other than Options Vested and Expected to Vest Outstanding Weighted Average Remaining Contractual Term
Vested and Expected to Vest, end of the period
Plan Name [Domain]
Plan Name
Contingent Consideration Type [Domain]
Contingent Consideration Type
Second target.
Second Target [Member]
Second Target
Class of Stock [Line Items]
Class Of Stock [Line Items]
Derivative Instrument [Axis]
Derivative Instrument
Income Tax Authority [Axis]
Income Tax Authority
Depreciation
Depreciation and amortization
Depreciation, Total
Lessee, Operating Lease, Term of Contract
Initial lease term
Valuation Allowance, Deferred Tax Asset, Increase (Decrease), Amount
Deferred tax asset, net change in total valuation allowance increase during period
Deferred Revenue Recognition Maturity Year
Deferred Revenue Recognition Maturity Year
Deferred revenue recognition maturity year.
Effective Income Tax Rate Reconciliation, State and Local Income Taxes, Percent
State tax, net of federal benefit
Schedule of Operating Leased Assets [Table]
Schedule Of Operating Leased Assets [Table]
Amortization of Intangible Assets
Amortization of intangible assets
Amortization expense of intangible assets
Amortization of Intangible Assets, Total
Effective income tax rate reconciliation net operating loss carryback.
Effective Income Tax Rate Reconciliation Net Operating Loss Carryback
Net operating loss carryback
Operating loss carryforwards amount to expire if not used.
Operating Loss Carryforwards Amount To Expire If Not Used
Operating loss carryforwards to expire if not utilized
Number of current and former officers named as defendants.
Number Of Current And Former Officers Named As Defendants
Number of current and former officers named as defendants
Issuance of common stock in follow-on offering, net of issuance costs
Stock Issued During Period, Value, New Issues
Loss Contingency, Lawsuit Filing Date
Lawsuit filed date
Issuance of Stock and Warrants for Services or Claims
Issuance of common stock in connection with UCSB sublicense fee
Revenue, Remaining Performance Obligation, Expected Timing of Satisfaction, Start Date [Axis]
Revenue, Remaining Performance Obligation, Expected Timing of Satisfaction, Start Date
Tabular disclosure of property plant and equipment estimated useful lives.
Property Plant And Equipment Estimated Useful Lives Table [Text Block]
Schedule of Useful Lives of Property and Equipment
Tenth year of lease term.
Tenth Year Of Lease Term [Member]
Tenth year of lease term
Share based compensation arrangement by share based payment award other than options exercisable weighted average remaining contractual term.
Share Based Compensation Arrangement by Share Based Payment Award Other than Options Exercisable Weighted Average Remaining Contractual Term
Exercisable, end of the period
Amgen products.
Amgen Products [Member]
Amgen Products
Indefinite-lived Intangible Assets (Excluding Goodwill)
Intangible assets, net
Indefinite-lived Intangible Assets (Excluding Goodwill), Total
Indefinite-lived Intangible Assets (Excluding Goodwill), Beginning Balance
Indefinite-lived Intangible Assets (Excluding Goodwill), Ending Balance
Open Tax Year
Open tax year
Number of accounting units.
Number Of Accounting Units
Number of accounting units
Share-based Payment Arrangement, Noncash Expense
Stock-based compensation expense
Share-based Payment Arrangement, Noncash Expense, Total
Prepaid Expense and Other Assets, Current
Prepaid expenses and other current assets
Share-based Payment Arrangement, Option, Activity [Table Text Block]
Schedule of Activity Under Company's Stock Option Plans
Long-Lived Tangible Asset [Domain]
Long-Lived Tangible Asset
Major customer [Member].
Major Customer [Member]
Major Customer
Current Federal Tax Expense (Benefit)
Federal
Effective Income Tax Rate Reconciliation, Other Adjustments, Percent
Other
Non-Employees Member.
Non Employees [Member]
Non-Employees
Loss contingency, answer and counterclaims by plaintiff filing date.
Loss Contingency Answer And Counterclaims By Plaintiff Filing Date
Loss contingency, answer and counterclaims by plaintiff filing date
Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercisable, Number
Options Exercisable, end of the period
Net Cash Provided by (Used in) Financing Activities
Net cash provided by financing activities
Loss contingency answer, affirmative defenses and counterclaims filing date.
Loss Contingency Answer Affirmative Defenses And Counterclaims Filing Date
Loss contingency, answer, affirmative defenses and counterclaims filing date
Share-based Compensation Arrangement by Share-based Payment Award, Maximum Employee Subscription Rate
Plan maximum percentage of eligible compensation to purchase shares
Commitments and Contingencies Disclosure [Abstract]
Right-of-Use Asset Obtained in Exchange for Operating Lease Liability
Right of use assets obtained in exchange for operating lease obligations
CD 71 agreement.
C D71 Agreement [Member]
CD71 Agreement
Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Vested in Period, Weighted Average Grant Date Fair Value
RSU's Released
Assets
Total assets
Summary of Income Tax Contingencies [Table Text Block]
Schedule of Reconciliation of Unrecognized Tax Benefits
Lessee, Operating Leases [Text Block]
Leases
Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercises in Period
Exercise of stock options, shares
Options exercised
Unrecognized Tax Benefits, Income Tax Penalties and Interest Accrued
Interest and penalties accrued
Unrecognized Tax Benefits, Income Tax Penalties and Interest Accrued, Total
Revenue, Product and Service [Extensible Enumeration]
Type of Revenue [Extensible List]
Litigation Case [Domain]
Litigation Case
Cash, cash equivalents and short term investments, amortized cost basis.
Cash Cash Equivalents And Short Term Investments Amortized Cost Basis
Amortized Cost
Amortized Cost
Statement [Line Items]
Statement [Line Items]
Liabilities and Equity
Total liabilities and stockholders' equity
Lessee operating lease liability payments due year five and thereafter.
Lessee Operating Lease Liability Payments Due Year Five And Thereafter
2026 and beyond
Property, Plant and Equipment [Abstract]
Statement of Cash Flows [Abstract]
Goodwill and intangible assets.
Goodwill And Intangible Assets [Line Items]
Goodwill And Intangible Assets [Line Items]
Summary of significant accounting policies.
Summary Of Significant Accounting Policies [Line Items]
Summary Of Significant Accounting Policies [Line Items]
Additional Paid-in Capital [Member]
Additional Paid-in Capital
Development regulatory and commercial milestone payments.
Development Regulatory And Commercial Milestone Payments [Member]
Development, Regulatory and Commercial Milestone Payments
Title of 12(b) Security
Title of 12(b) Security
Comprehensive Income (Loss), Net of Tax, Attributable to Parent
Total comprehensive loss
Total comprehensive loss
Right to expand the number of additional collaboration target.
Right To Expand Number Of Additional Collaboration Target
Right to expand the number of additional collaboration target
Premium on issuance of shares allocated to common stock.
Premium On Issuance Of Shares Allocated To Common Stock
Portion of transaction price allocated to premium on sale of common stock
Entity Well-known Seasoned Issuer
Entity Well-known Seasoned Issuer
Award Type [Domain]
Award Type
Share-based Compensation Arrangement by Share-based Payment Award, Award Vesting Rights, Percentage
Options granted generally vest percent
Fair Value Hierarchy and NAV [Axis]
Fair Value Hierarchy and NAV
Collaborative Arrangement [Member]
Collaborative Arrangement
Share-based Compensation Arrangement by Share-based Payment Award, Expiration Period
Stock option expiration period
Cash paid for amounts included in measurement of lease liabilities.
Cash Paid For Amounts Included In Measurement Of Lease Liabilities [Abstract]
Cash paid for amounts included in the measurement of lease liabilities
Investment Income, Interest
Interest income
Payments of sublicense fees.
Payments Of Sublicense Fees
Sublicense fees paid
Property, Plant and Equipment [Table Text Block]
Summary of Property and Equipment, Net
Probody Platform Intangible Asset
Probody Platform Intangible Asset [Member]
Probody platform intangible asset member.
Fair Value, Inputs, Level 1 [Member]
Level I
Research and Development Arrangement, Contract to Perform for Others, Type [Domain]
Research and Development Arrangement, Contract to Perform for Others, Type
Lessee, Operating Lease, Liability, to be Paid, Year Four
2025
Effective Income Tax Rate Reconciliation, Change in Deferred Tax Assets Valuation Allowance, Percent
Change in valuation allowance
Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested and Expected to Vest, Outstanding, Weighted Average Exercise Price
Options vested and expected to vest, end of the period
Income Tax Contingency [Table]
Income Tax Contingency [Table]
Deferred Tax Liabilities, Net
Net deferred income tax liabilities
Deferred Tax Liabilities, Net, Total
Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Gross
Options granted
Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Aggregate Intrinsic Value, Outstanding
Balances, end of the period
RSU's Awarded, Grant date fair value
Entity Current Reporting Status
Entity Current Reporting Status
Revenue, Remaining Performance Obligation, Amount
Revenue recognition upon performance obligation
Noncash Investing and Financing Items [Abstract]
Supplemental disclosures of noncash investing items:
Entity Voluntary Filers
Entity Voluntary Filers
Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Risk Free Interest Rate, Minimum
Risk-free interest rate, minimum
Scenario [Domain]
Scenario
Money Market Funds [Member]
Money market funds
Documents Incorporated by Reference [Text Block]
Documents Incorporated by Reference
Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Grants in Period, Weighted Average Grant Date Fair Value
RSU's Awarded
Transferred over Time [Member]
Transferred over Time
Debt Securities Available For Sale Maturity Period
Debt securities, available for sale, maturity period.
Debt securities, available for sale, maturity period
Drug application for CTLA-4.
Drug Application For C T L A4 [Member]
New Drug Application for CTLA-4
Share-based Payment Arrangement, Expensed and Capitalized, Amount [Table Text Block]
Total Stock-based Compensation Recognized
Retirement Benefits [Abstract]
EGFR Products.
E G F R Products [Member]
EGFR Products
Percentage of remaining maintenance fees outstanding.
Percentage Of Remaining Maintenance Fees Outstanding
Percentage of remaining maintenance fees outstanding
Lock Up Period For Share Transaction Under Collaboration And License Agreement
Lock-up period for share disposal
Lock-up period for share transaction under collaboration and license agreement.
Shares issued average price per share.
Shares Issued Average Price Per Share
Average price
Deferred State and Local Income Tax Expense (Benefit)
State
AOCI Attributable to Parent [Member]
Accumulated Other Comprehensive Income/(Loss)
Auditor Firm Id
Auditor Firm ID
Weighted average remaining lease term.
Weighted Average Remaining Lease Term [Abstract]
Weighted-average remaining lease term (in years)
Income Statement Location [Domain]
Income Statement Location
Share-based Payment Arrangement, Tranche One [Member]
Share Based Compensation Award Tranche One
Securities class action lawsuit.
Securities Class Action Lawsuit [Member]
Securities Class Action Lawsuit
UNITED STATES
U.S
Increments of extended collaboration target research times.
Increments Of Extended Collaboration Target Research Times
Times of increments for extended collaboration target research time
Upfront license payment.
Upfront License Payment
Upfront license payment
Auditor Name
Auditor Name
Cumulative Effect, Period of Adoption, Adjustment [Member]
Cumulative Effect, Period of Adoption, Adjustment
Supplemental balance sheet information related to leases.
Supplemental Balance Sheet Information Related To Leases [Abstract]
Supplemental balance sheet information related to leases:
Preferred Stock, Shares Authorized
Convertible Preferred stock, shares authorized
Preferred stock, shares authorized
Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercisable, Weighted Average Exercise Price
Options Exercisable, end of the period
Construction in Progress, Gross
Construction in progress
Minimum [Member]
Minimum
Minimum
Increase in common stock capital shares reserved for future issuance
Increase in Common Stock Capital Shares Reserved For Future Issuance
Increase in common stock capital shares reserved for future issuance
Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested and Expected to Vest, Outstanding, Weighted Average Remaining Contractual Term
Options vested and expected to vest, end of the period
Vested and Expected to Vest - December 31, 2021
Cash and Cash Equivalents [Abstract]
Period of time to terminate license after notice date.
License Termination Period
License termination period
Stock Issued During Period, Value, Stock Options Exercised
Exercise of stock options
Percentage of change in ownership.
Percentage Of Change In Ownership
Percentage of change in ownership
Debt Securities, Available-for-Sale, Fair Value, Maturity, Allocated and Single Maturity Date, Year One
Contractual maturities of greater than twelve months
Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Grants in Period
RSU's Awarded
Granted
Timing of Transfer of Good or Service [Domain]
Timing of Transfer of Good or Service
Lessee, Operating Lease, Liability, Payment, Due [Abstract]
Maturity of operating lease liabilities
Underwritten public offering.
Underwritten Public Offering [Member]
Underwritten Public Offering
Document Annual Report
Document Annual Report
Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Aggregate Intrinsic Value, Vested
RSU's Released
Operating loss carryforwards amount not subject to expiration.
Operating Loss Carryforwards Amount Not Subject To Expiration
Operating loss carryforwards not subject to expiration
Deferred Tax Assets, Valuation Allowance
Less: valuation allowance
Deferred Tax Assets, Valuation Allowance, Total
Proceeds, Issuance of Shares, Share-based Payment Arrangement, Including Option Exercised
Proceeds from employee stock purchase plan and exercise of stock options
Proceeds, Issuance of Shares, Share-based Payment Arrangement, Including Option Exercised, Total
Net Cash Provided by (Used in) Financing Activities [Abstract]
Cash flows from financing activities:
Aggregate collaboration transaction amount.
Aggregate Collaboration Transaction Amount
Total transaction price
ImmunoGen, Inc.
Immuno Gen Inc [Member]
Immuno Gen Inc
ImmunoGen
Goodwill, Impairment Loss
Impairment of goodwill
Entity Filer Category
Entity Filer Category
Income Tax, Policy [Policy Text Block]
Income Taxes
Contingent milestone payments no longer eligible to receive.
Contingent Milestone Payments No Longer Eligible To Receive
Contingent milestone payments, no longer eligible to receive
Document Fiscal Year Focus
Document Fiscal Year Focus
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]
Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items]
Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested and Expected to Vest, Outstanding, Number
Options vested and expected to vest, end of the period
Vested and Expected to Vest - December 31, 2021
Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table]
Schedule Of Antidilutive Securities Excluded From Computation Of Earnings Per Share [Table]
Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Weighted Average Grant Date Fair Value
Weighted average grant date fair value, options granted
RSU's Awarded
Loss Contingency, Name of Plaintiff
Name of plaintiff
Retained Earnings (Accumulated Deficit)
Accumulated deficit
Increase in accumulated deficit balance
Retained Earnings (Accumulated Deficit), Total
Retained Earnings (Accumulated Deficit), Beginning Balance
Retained Earnings (Accumulated Deficit), Ending Balance
Income Tax Disclosure [Text Block]
Income Taxes
Letters of Credit Outstanding, Amount
Letter of credit outstanding, amount
Two thousand fifteen stock incentive plan.
Two Thousand Fifteen Stock Incentive Plan [Member]
2015 Plan
Schedule of goodwill and intangible assets.
Schedule Of Goodwill And Intangible Assets [Table]
Schedule Of Goodwill And Intangible Assets [Table]
Fair Value Disclosures [Abstract]
Property, Plant and Equipment Disclosure [Text Block]
Property and Equipment
Maximum [Member]
Maximum
Contract with Customer, Contract Asset, Contract Liability, and Receivable [Table Text Block]
Summary of Contract Liabilities
Entity Central Index Key
Entity Central Index Key
Loss Contingency, Estimate of Possible Loss
Loss contingency claim amount
Cash and Cash Equivalents, Restricted Cash and Cash Equivalents, Policy [Policy Text Block]
Restricted Cash
Fair value of common stock issued.
Fair Value Of Common Stock Issued
Fair value of common stock issued
License payment term.
License Payment Term
License payment term
Performance restricted stock units.
Performance Restricted Stock Units [Member]
PSU's
Operating Lease, Expense
Rent expense
Cash and Cash Equivalents, Policy [Policy Text Block]
Cash and Cash Equivalents
Entity Tax Identification Number
Entity Tax Identification Number
Equity Component [Domain]
Equity Component
Preferred Stock, Par or Stated Value Per Share
Convertible Preferred stock, par value
Preferred stock, par value
Property, Plant and Equipment, Policy [Policy Text Block]
Property and Equipment, net
Future contingent milestone payment receivable.
Contingent Milestone Payments Receivable
Contingent milestone payments receivable
Deferred tax assets lease liability.
Deferred Tax Assets Lease Liability
Lease liability
Initial Application Period Cumulative Effect Transition [Domain]
Initial Application Period Cumulative Effect Transition
Income Tax Authority [Domain]
Income Tax Authority
Payment of upfront fees.
Payment Of Upfront Fees
Payment of upfront fees
Share-based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Period for Recognition
Unrecognized stock-based compensation cost, period for recognition
Third and fourth targets.
Third And Fourth Targets [Member]
Third And Fourth Immuno-Oncology Targets
Increase (Decrease) in Accounts Receivable
Accounts receivable
Change in Accounting Principle, Accounting Standards Update, Adoption Date
Change in accounting principle, accounting standards update, adoption date
Subsequent Events [Abstract]
Leasehold Improvements [Member]
Leasehold improvements
Share based compensation arrangement by share based payment award other than options vested and expected to vest outstanding number.
Share Based Compensation Arrangement By Share Based Payment Award Other Than Options Vested and Expected to Vest Outstanding Number
Vested and Expected to Vest, end of the period
Statement [Table]
Statement [Table]
Operating Lease, Weighted Average Remaining Lease Term
Operating lease
Entity File Number
Entity File Number
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Contingent payments receivable profit split on sales.
Contingent Payments Receivable Profit Split On Sales
Profit split on U.S. sales
Retained Earnings [Member]
Accumulated Deficit
Shares Issued, Price Per Share
Fair value of common stock price per share
Common stock price, per share
Accounting Standards Update [Domain]
Accounting Standards Update
Accounting Standards Update [Axis]
Accounting Standards Update
Revenue from Contract with Customer, Excluding Assessed Tax
Revenue recognized from collaborative arrangement
Revenues
Revenue from Contract with Customer, Excluding Assessed Tax, Total
Estimated research service period.
Estimated Research Service Period
Estimated research service period
Payments of Stock Issuance Costs
Underwriting discounts and commissions and offering expenses
Underwriting discounts and commissions and offering expenses
Increase (Decrease) in Accounts Payable
Accounts payable
Increase (Decrease) in Accounts Payable, Total
Shares, Issued
Ending balance, shares
Beginning balance, shares
Basis of Presentation and Significant Accounting Policies [Text Block]
Basis of Presentation and Summary of Significant Accounting Policies
Liabilities, Current [Abstract]
Current liabilities:
Share-based Payment Arrangement [Text Block]
Stock-based Compensation
Schedule of Intangible Assets
Schedule of Intangible Assets and Goodwill [Table Text Block]
Commitments and Contingencies Disclosure [Text Block]
Commitments and Contingencies
Probody technology.
Probody Technology [Member]
Probody technology
Operating Lease, Liability
Present value of lease liabilities
Total operating lease liabilities
Furniture and Fixtures, Gross
Furniture and fixtures
Common Stock [Member]
Common Stock
Property, Plant and Equipment, Gross
Total property and equipment
Property, Plant and Equipment, Gross, Beginning Balance
Property, Plant and Equipment, Gross, Ending Balance
Intangible Assets
Goodwill and Intangible Assets Disclosure [Text Block]
Computer equipment and software.
Computer Equipment And Software [Member]
Computer equipment and software
Accrued Professional Fees, Current
Legal and professional expenses
Entity Public Float
Entity Public Float
Cover [Abstract]
Credit Facility [Domain]
Credit Facility
Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Nonvested, Weighted Average Grant Date Fair Value, Beginning Balance
Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Nonvested, Weighted Average Grant Date Fair Value
Balances, end of the period
Asset Class [Axis]
Asset Class
Deferred Tax Assets, Tax Credit Carryforwards, Research
Research and development credits
Estimated premium on issuance of shares.
Estimated Premium On Issuance Of Shares
Estimated premium on the stock sold
Statement of Stockholders' Equity [Abstract]
Property, Plant and Equipment [Table]
Schedule Of Property Plant And Equipment [Table]
Concentration Risk [Table]
Concentration Risk [Table]
Number of Operating Segments
Number of operating segments
Share-based Payment Arrangement [Abstract]
Research and Development Arrangement, Contract to Perform for Others [Line Items]
License Agreement [Line Items]
Share based compensation arrangement by share based payment award other than options vested and expected to vest aggregate intrinsic value.
Share Based Compensation Arrangement by Share Based Payment Award Other than Options Vested and Expected to Vest Aggregate Intrinsic Value
Vested and Expected to Vest, end of the period
RSU's
Restricted Stock Units (RSUs) [Member]
Cash, Cash Equivalents, and Short-term Investments
Aggregate Fair Value
Cash, Cash Equivalents, and Short-term Investments, Total
Long-Lived Tangible Asset [Axis]
Long-Lived Tangible Asset
Cash, cash equivalents and short term investments, accumulated gross unrealized loss before tax.
Cash Cash Equivalents And Short Term Investments Accumulated Gross Unrealized Loss Before Tax
Gross Unrealized Holding Losses
Other Accrued Liabilities, Current
Other accrued expenses
Document Transition Report
Document Transition Report
Letter of Credit [Member]
Letter of Credit
Lessee, Operating Lease, Renewal Term
Extended lease term
Share-based Payment Arrangement, Noncash Expense [Abstract]
Stock-based compensation expense:
Research and Development Expense
Research and development
Research and development expense
Research and Development Expense, Total
Maximum improvement allowance.
Maximum Improvement Allowance
Maximum one-time improvement allowance
Contract with Customer, Liability, Noncurrent
Deferred revenue, net of current portion
Milestone payment payable.
Milestone Payment Payable
Milestone payments payable
Dividends, Common Stock
Dividends on common stock
Dividends, Common Stock, Total
Computer equipment and software gross.
Computer Equipment And Software Gross
Computer equipment and software
Share-based Payment Arrangement, Expense
Stock-based compensation expense
Stock-based compensation expense
Initial Application Period Cumulative Effect Transition [Axis]
Initial Application Period Cumulative Effect Transition
Goodwill and Intangible Assets, Policy [Policy Text Block]
Goodwill and Intangible Assets
Operating leases rent expense annual base rent.
Operating Leases Rent Expense Annual Base Rent
Annual lease rent
Statement of Financial Position [Abstract]
Sublicense agreement.
Sublicense Agreement [Member]
Sublicense Agreement
Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Expected Dividend Rate
Dividend yield
RSU's Vested
Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Vested in Period
Number of collaboration agreements.
Number Of Collaboration Agreements
Number of collaboration agreements
Accrued liabilities
Deferred Tax Assets, Tax Deferred Expense, Reserves and Accruals, Accrued Liabilities
Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents, Period Increase (Decrease), Excluding Exchange Rate Effect
Net increase (decrease) in cash, cash equivalents and restricted cash
Deferred Tax Assets, Goodwill and Intangible Assets
Intangible assets
Lease Contractual Term [Axis]
Lease Contractual Term
Estimated research service termination date.
Estimated Research Service Termination Date
Estimated research service termination date
Percentage of net Income or net losses related to development and commercialization costs.
Percentage Of Net Income Or Net Losses Related To Development And Commercialization Costs
Percentage of net profits or net losses related to development and commercialization costs
Effective Income Tax Rate Reconciliation, at Federal Statutory Income Tax Rate, Percent
U.S. federal taxes at statutory rate
Stockholders' Equity Attributable to Parent [Abstract]
Stockholders' equity
Nature of Operations [Text Block]
Description of the Business
Share-based Compensation Arrangement by Share-based Payment Award, Options, Additional Disclosures [Abstract]
Options Outstanding, Weighted- Average Remaining Contractual Life (years)
Average Remaining Contractual Life (years)
Lease Contractual Term [Domain]
Lease Contractual Term
Additional
Contract with customer liability additions.
Contract With Customer Liability Additions
Additions to deferred revenue
Contract with customer liability maturity month and year.
Contract With Customer Liability Maturity Month And Year
Deferred revenue recognition maturity month and year
Research and development service fees.
Research And Development Service Fees
Research and development service fees
Share-based Compensation Arrangements by Share-based Payment Award, Restricted Stock Units, Vested and Expected to Vest [Table Text Block]
Schedule of Company's TRSU Activities
Additional sublicense fees.
Additional Sublicense Fees
Additional sublicense fees
Share-based Compensation Arrangements by Share-based Payment Award, Options, Exercises in Period, Weighted Average Exercise Price
Options exercised
Early exercise of employee options.
Early Exercise Of Employee Options [Member]
Early Exercise of Employee Options
Increase (Decrease) in Operating Capital [Abstract]
Changes in operating assets and liabilities
Option period granted to underwriters to purchase additional shares.
Option Period Granted To Underwriters To Purchase Additional Shares
Period granted to underwriters to purchase additional shares
Lessee, Operating Lease, Liability, to be Paid, Year Three
2024
Entity Common Stock, Shares Outstanding
Entity Common Stock, Shares Outstanding
Effective Income Tax Rate Reconciliation, Nondeductible Expense, Share-based Payment Arrangement, Percent
Stock compensation
Common Stock, Capital Shares Reserved for Future Issuance
Common stock, capital shares reserved for future issuance
Total
Award Type [Axis]
Award Type
Entity Shell Company
Entity Shell Company
Liabilities and Equity [Abstract]
Liabilities and Stockholders' Equity
Retirement Benefits [Text Block]
Defined Contribution Plan
ICFR Auditor Attestation Flag
ICFR Auditor Attestation Flag
Entity Incorporation, State or Country Code
Entity Incorporation, State or Country Code
Stock Issued During Period, Value, Employee Stock Purchase Plan
Issuance of common stock under the Employee Stock Purchase Plan
Earnings Per Share [Text Block]
Net Loss Per Share
Number of research targets selected.
Number Of Research Targets Selected
Number of research targets selected
Counterparty Name [Domain]
Counterparty Name
Deferred Tax Liabilities, Leasing Arrangements
Right-of-use assets
Leasehold Improvements, Gross
Leasehold improvements
Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Nonvested, Number of Shares [Roll Forward]
Amendment Flag
Amendment Flag
Seattle genetics agreement.
Seattle Genetics Agreement [Member]
Seattle Genetics Agreement
Schedule Of Stock By Class [Table]
Schedule of Stock by Class [Table]
Product and Service [Axis]
Product and Service
Schedule of Finite-Lived Intangible Assets [Table]
Schedule Of Finite Lived Intangible Assets [Table]
Other Nonoperating Income (Expense)
Other expense, net
Other Nonoperating Income (Expense), Total
Increase (Decrease) in Contract with Customer, Liability
Deferred revenue
Cash and Cash Equivalents, at Carrying Value
Cash and cash equivalents
Cash and Cash Equivalents, at Carrying Value, Total
Cash and Cash Equivalents, at Carrying Value, Beginning Balance
Cash and Cash Equivalents, at Carrying Value, Ending Balance
New Accounting Pronouncements, Policy [Policy Text Block]
Adopted Accounting Pronouncements
Summary of significant accounting policies.
Summary Of Significant Accounting Policies [Table]
Summary Of Significant Accounting Policies [Table]
Operating Lease, Liability, Current, Statement of Financial Position [Extensible Enumeration]
Operating Lease, Liability, Current, Statement of Financial Position [Extensible List]
Tax Credit Carryforward, Amount
Tax credit carry forwards
Number of targets selected.
Number Of Targets Selected
Number of targets selected
Share-based Payment Arrangement, Nonvested Award, Option, Cost Not yet Recognized, Amount
Unrecognized compensation expense, options granted
Income Taxes Paid, Net
Cash paid for income taxes
Income Taxes Paid, Net, Total
Subsequent Events [Text Block]
Subsequent Events
Proceeds from Collaborators
Upfront payment received
Property, Plant and Equipment [Line Items]
Property Plant And Equipment [Line Items]
Other Assets, Noncurrent
Other assets
Other Assets, Noncurrent, Total
Other comprehensive income (loss)
OCI, Debt Securities, Available-for-Sale, Gain (Loss), after Adjustment and Tax
Unrealized gain (loss) on short-term investments, net of tax
OCI, Debt Securities, Available-for-Sale, Gain (Loss), after Adjustment and Tax, Total
Increase (decrease) in accrued liabilities, income tax payable and other liabilities noncurrent.
Increase Decrease In Accrued Liabilities Income Tax Payable And Other Liabilities Noncurrent
Accrued liabilities, income tax payable and other long-term liabilities
Collaborative Arrangement and Arrangement Other than Collaborative [Axis]
Collaborative Arrangement and Arrangement Other than Collaborative
Geographical [Domain]
Geographical
Customer [Domain]
Customer
Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercisable, Intrinsic Value
Options Exercisable—December 31, 2020
Ending Exercisable - December 31, 2021
Share-based Compensation Arrangement by Share-based Payment Award, Purchase Price of Common Stock, Percent
Estimated fair value of the shares on the date of grant
Schedules of Concentration of Risk, by Risk Factor [Table Text Block]
Schedule of Customers and Collaboration Partners who Represent 10% or More of Total Revenue During Each Period Presented or Net Accounts Receivable Balance
Upfront fee received.
Upfront Fee Received
Upfront payment received
Difference between Revenue Guidance in Effect before and after Topic 606 [Member]
Adjustments
Sale of Stock [Axis]
Sale of Stock
Finite-Lived Intangible Assets, Major Class Name [Domain]
Finite-Lived Intangible Assets, Major Class Name
Two Thousand Nineteen Stock Incentive Plan Member.
Two Thousand Nineteen Stock Incentive Plan [Member]
2019 Plan
Collaboration target research term.
Collaboration Target Research Term
Collaboration target research term
Components of Deferred Tax Assets and Liabilities [Abstract]
Fair Value Disclosures [Text Block]
Fair Value Measurements and Investments
Cumulative Effect, Period of Adoption [Domain]
Cumulative Effect, Period of Adoption
Share-based Payment Arrangement, Nonvested Award, Excluding Option, Cost Not yet Recognized, Amount
Unrecognized stock-based compensation cost
Proceeds from Issuance of Common Stock
Proceeds from issuance of common stock, net of issuance costs
Common stock, value of shares issued in connection with agreement