0001501989 2025-01-01 2025-12-31 0001501989 ctmx:Tranche1Member ctmx:SeanAMcCarthyDPhilMember 2025-02-05 0001501989 ctmx:Tranche2Member ctmx:SeanAMcCarthyDPhilMember 2025-02-05 0001501989 ctmx:Tranche1Member ctmx:ChrisOgdenMember 2025-02-05 0001501989 ctmx:Tranche2Member ctmx:ChrisOgdenMember 2025-02-05 0001501989 2024-01-01 2024-12-31 0001501989 2023-01-01 2023-12-31 0001501989 ecd:EqtyAwrdsInSummryCompstnTblForAplblYrMember ecd:PeoMember 2025-01-01 2025-12-31 0001501989 ecd:EqtyAwrdsAdjsExclgValRprtdInSummryCompstnTblMember ecd:PeoMember 2025-01-01 2025-12-31 0001501989 ecd:EqtyAwrdsInSummryCompstnTblForAplblYrMember ecd:NonPeoNeoMember 2025-01-01 2025-12-31 0001501989 ecd:EqtyAwrdsAdjsExclgValRprtdInSummryCompstnTblMember ecd:NonPeoNeoMember 2025-01-01 2025-12-31 0001501989 ecd:YrEndFrValOfEqtyAwrdsGrntdInCvrdYrOutsdngAndUnvstdMember ecd:PeoMember 2025-01-01 2025-12-31 0001501989 ecd:ChngInFrValOfOutsdngAndUnvstdEqtyAwrdsGrntdInPrrYrsMember ecd:PeoMember 2025-01-01 2025-12-31 0001501989 ecd:VstngDtFrValOfEqtyAwrdsGrntdAndVstdInCvrdYrMember ecd:PeoMember 2025-01-01 2025-12-31 0001501989 ecd:ChngInFrValAsOfVstngDtOfPrrYrEqtyAwrdsVstdInCvrdYrMember ecd:PeoMember 2025-01-01 2025-12-31 0001501989 ecd:FrValAsOfPrrYrEndOfEqtyAwrdsGrntdInPrrYrsFldVstngCondsDrngCvrdYrMember ecd:PeoMember 2025-01-01 2025-12-31 0001501989 ecd:YrEndFrValOfEqtyAwrdsGrntdInCvrdYrOutsdngAndUnvstdMember ecd:NonPeoNeoMember 2025-01-01 2025-12-31 0001501989 ecd:ChngInFrValOfOutsdngAndUnvstdEqtyAwrdsGrntdInPrrYrsMember ecd:NonPeoNeoMember 2025-01-01 2025-12-31 0001501989 ecd:VstngDtFrValOfEqtyAwrdsGrntdAndVstdInCvrdYrMember ecd:NonPeoNeoMember 2025-01-01 2025-12-31 0001501989 ecd:ChngInFrValAsOfVstngDtOfPrrYrEqtyAwrdsVstdInCvrdYrMember ecd:NonPeoNeoMember 2025-01-01 2025-12-31 0001501989 ecd:FrValAsOfPrrYrEndOfEqtyAwrdsGrntdInPrrYrsFldVstngCondsDrngCvrdYrMember ecd:NonPeoNeoMember 2025-01-01 2025-12-31 shares iso4217:USD shares iso4217:USD pure CytomX Therapeutics, Inc. true <div class="BRDSX_h3" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt; font-style: italic; font-weight: bold; margin-top: 6.75pt; margin-left: 0pt; text-align: left;">Equity Award Timing Policies and Practices </div><div class="BRDSX_para" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt; margin-top: 6pt; margin-left: 0pt; text-indent: 20pt; text-align: justify;">We generally grant equity awards at regularly scheduled Board of Director or Compensation Committee meetings. We do not grant equity awards in anticipation of the release of material nonpublic information and we do not time the release of material nonpublic information for the purpose of affecting the value of executive compensation. In the event material nonpublic information becomes known to the Board of Directors or Compensation Committee before granting an equity award, the Board of Directors or Compensation Committee will consider such information and use its business judgment to determine whether to delay the grant of equity to avoid any appearance of impropriety. </div><div class="BRDSX_para" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt; margin-top: 6pt; margin-left: 0pt; text-indent: 20pt; text-align: justify;">The following table sets forth information regarding stock option grants made to the named executive officers during fiscal year 2025 within the period commencing four business days prior to or the one business day following our filing of a Form 8-K on February 3, 2025, that discloses non-public information, as required under Item 4.02(x) of Regulation S-K. We did not view the information in the Form 8-K as material.</div><table cellpadding="0" class="BRDSX_fintab" style="margin-top: 4pt; width: 468pt; margin-left: auto; margin-right: auto; border-spacing: 0px;"><tr class="BRDSX_boxspacer"><td style="height: 6pt; width: 120pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 7.27pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 7.27pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 38.87pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 7.27pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 7.27pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 38.75pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 7.27pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 7.27pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 35.17pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 7.27pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 7.27pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 38.87pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 7.27pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 7.27pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 123.67pt;"><div style="font-size: 1pt;"> </div></td></tr><tr class="BRDSX_header"><td style="width: 120pt; padding-bottom: 2.38pt; text-align: left; vertical-align: bottom; border-bottom: 1pt solid #000000;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; margin-left: 0pt; text-align: left;">Name</div></td><td style="width: 7.27pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 7.27pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 38.87pt; padding-bottom: 2.38pt; text-align: left; vertical-align: bottom; border-bottom: 1pt solid #000000;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; white-space: nowrap; text-align: center;">Grant Date</div></td><td style="width: 7.27pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 7.27pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 38.75pt; padding-bottom: 2.38pt; text-align: left; vertical-align: bottom; border-bottom: 1pt solid #000000;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; white-space: nowrap; text-align: center;">Number of<br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; white-space: nowrap; text-align: center;">Securities<br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; white-space: nowrap; text-align: center;">Underlying<br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; white-space: nowrap; text-align: center;">the Award</div></td><td style="width: 7.27pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 7.27pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 35.17pt; padding-bottom: 2.38pt; text-align: left; vertical-align: bottom; border-bottom: 1pt solid #000000;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; white-space: nowrap; text-align: center;">Exercise <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; white-space: nowrap; text-align: center;">Price of <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; white-space: nowrap; text-align: center;">the Award <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; white-space: nowrap; text-align: center;">($/Sh) </div></td><td style="width: 7.27pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 7.27pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 38.87pt; padding-bottom: 2.38pt; text-align: left; vertical-align: bottom; border-bottom: 1pt solid #000000;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; white-space: nowrap; text-align: center;">Grant Date<br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; white-space: nowrap; text-align: center;">Fair Value<br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; white-space: nowrap; text-align: center;">of the<br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; white-space: nowrap; text-align: center;">Award⁽³⁾</div></td><td style="width: 7.27pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 7.27pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 123.67pt; padding-bottom: 2.38pt; text-align: left; vertical-align: bottom; border-bottom: 1pt solid #000000;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; white-space: nowrap; text-align: center;">Percentage Change in the Closing <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; white-space: nowrap; text-align: center;">Market Price of the Securities <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; white-space: nowrap; text-align: center;">Underlying the Award Between the <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; white-space: nowrap; text-align: center;">Trading Day Ending Immediately <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; white-space: nowrap; text-align: center;">Prior to the Disclosure of MNPI and <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; white-space: nowrap; text-align: center;">the Trading Day Beginning <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; white-space: nowrap; text-align: center;">Immediately Following the <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; white-space: nowrap; text-align: center;">Disclosure of MNPI </div></td></tr><tr><td style="width: 120pt; padding-top: 2.01pt; padding-bottom: 1.38pt; text-align: left; vertical-align: bottom; background-color: #CCEEFF;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt; margin-top: 0pt; margin-left: 0pt; text-align: left;">Sean A. McCarthy, D. Phil</div></td><td style="width: 7.27pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 7.27pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 38.87pt; padding-top: 2.01pt; padding-bottom: 1.38pt; text-align: center; vertical-align: bottom; background-color: #CCEEFF; white-space: nowrap;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt; margin-top: 0pt; margin-left: 1.65pt; text-align: left;">2/5/2025</div></td><td style="width: 7.27pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 7.27pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 38.75pt; padding-top: 2.01pt; padding-bottom: 1.38pt; text-align: center; vertical-align: bottom; background-color: #CCEEFF; white-space: nowrap;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt; margin-top: 0pt; margin-left: 0.01pt; text-align: left;">800,000⁽¹⁾</div></td><td style="width: 7.27pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 7.27pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 35.17pt; padding-top: 2.01pt; padding-bottom: 1.38pt; text-align: center; vertical-align: bottom; background-color: #CCEEFF; white-space: nowrap;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt; margin-top: 0pt; margin-left: 3.85pt; text-align: left;">$0.864</div></td><td style="width: 7.27pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 7.27pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 38.87pt; padding-top: 2.01pt; padding-bottom: 1.38pt; text-align: center; vertical-align: bottom; background-color: #CCEEFF; white-space: nowrap;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt; margin-top: 0pt; margin-left: 0.69pt; text-align: left;">$691,200</div></td><td style="width: 7.27pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 7.27pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 123.67pt; padding-top: 2.01pt; padding-bottom: 1.38pt; text-align: center; vertical-align: bottom; background-color: #CCEEFF; white-space: nowrap;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt; margin-top: 0pt; margin-left: 59.33pt; text-align: left;">0%</div></td></tr><tr><td style="width: 120pt; padding-top: 1.01pt; padding-bottom: 1.38pt; text-align: left; vertical-align: bottom;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt; margin-top: 0pt; margin-left: 0pt; text-align: left;">Sean A. McCarthy, D. Phil</div></td><td style="width: 7.27pt;"><div style="font-size: 1pt;"> </div></td><td style="width: 7.27pt;"><div style="font-size: 1pt;"> </div></td><td style="width: 38.87pt; padding-top: 1.01pt; padding-bottom: 1.38pt; text-align: center; vertical-align: bottom; white-space: nowrap;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt; margin-top: 0pt; margin-left: 1.65pt; text-align: left;">2/5/2025</div></td><td style="width: 7.27pt;"><div style="font-size: 1pt;"> </div></td><td style="width: 7.27pt;"><div style="font-size: 1pt;"> </div></td><td style="width: 38.75pt; padding-top: 1.01pt; padding-bottom: 1.38pt; text-align: center; vertical-align: bottom; white-space: nowrap;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt; margin-top: 0pt; margin-left: 0.01pt; text-align: left;">390,000⁽²⁾</div></td><td style="width: 7.27pt;"><div style="font-size: 1pt;"> </div></td><td style="width: 7.27pt;"><div style="font-size: 1pt;"> </div></td><td style="width: 35.17pt; padding-top: 1.01pt; padding-bottom: 1.38pt; text-align: center; vertical-align: bottom; white-space: nowrap;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt; margin-top: 0pt; margin-left: 3.85pt; text-align: left;">$0.864</div></td><td style="width: 7.27pt;"><div style="font-size: 1pt;"> </div></td><td style="width: 7.27pt;"><div style="font-size: 1pt;"> </div></td><td style="width: 38.87pt; padding-top: 1.01pt; padding-bottom: 1.38pt; text-align: center; vertical-align: bottom; white-space: nowrap;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt; margin-top: 0pt; margin-left: 0.69pt; text-align: left;">$336,960</div></td><td style="width: 7.27pt;"><div style="font-size: 1pt;"> </div></td><td style="width: 7.27pt;"><div style="font-size: 1pt;"> </div></td><td style="width: 123.67pt; padding-top: 1.01pt; padding-bottom: 1.38pt; text-align: center; vertical-align: bottom; white-space: nowrap;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt; margin-top: 0pt; margin-left: 59.33pt; text-align: left;">0%</div></td></tr><tr><td style="width: 120pt; padding-top: 1.01pt; padding-bottom: 1.38pt; text-align: left; vertical-align: bottom; background-color: #CCEEFF;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt; margin-top: 0pt; margin-left: 0pt; text-align: left;">Chris Ogden</div></td><td style="width: 7.27pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 7.27pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 38.87pt; padding-top: 1.01pt; padding-bottom: 1.38pt; text-align: center; vertical-align: bottom; background-color: #CCEEFF; white-space: nowrap;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt; margin-top: 0pt; margin-left: 1.65pt; text-align: left;">2/5/2025</div></td><td style="width: 7.27pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 7.27pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 38.75pt; padding-top: 1.01pt; padding-bottom: 1.38pt; text-align: center; vertical-align: bottom; background-color: #CCEEFF; white-space: nowrap;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt; margin-top: 0pt; margin-left: 0.01pt; text-align: left;">225,000⁽¹⁾</div></td><td style="width: 7.27pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 7.27pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 35.17pt; padding-top: 1.01pt; padding-bottom: 1.38pt; text-align: center; vertical-align: bottom; background-color: #CCEEFF; white-space: nowrap;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt; margin-top: 0pt; margin-left: 3.85pt; text-align: left;">$0.864</div></td><td style="width: 7.27pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 7.27pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 38.87pt; padding-top: 1.01pt; padding-bottom: 1.38pt; text-align: center; vertical-align: bottom; background-color: #CCEEFF; white-space: nowrap;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt; margin-top: 0pt; margin-left: 0.69pt; text-align: left;">$194,400</div></td><td style="width: 7.27pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 7.27pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 123.67pt; padding-top: 1.01pt; padding-bottom: 1.38pt; text-align: center; vertical-align: bottom; background-color: #CCEEFF; white-space: nowrap;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt; margin-top: 0pt; margin-left: 59.33pt; text-align: left;">0%</div></td></tr><tr><td style="width: 120pt; padding-top: 1.01pt; text-align: left; vertical-align: bottom;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt; margin-top: 0pt; margin-left: 0pt; text-align: left;">Chris Ogden</div></td><td style="width: 7.27pt;"><div style="font-size: 1pt;"> </div></td><td style="width: 7.27pt;"><div style="font-size: 1pt;"> </div></td><td style="width: 38.87pt; padding-top: 1.01pt; text-align: center; vertical-align: bottom; white-space: nowrap;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt; margin-top: 0pt; margin-left: 1.65pt; text-align: left;">2/5/2025</div></td><td style="width: 7.27pt;"><div style="font-size: 1pt;"> </div></td><td style="width: 7.27pt;"><div style="font-size: 1pt;"> </div></td><td style="width: 38.75pt; padding-top: 1.01pt; text-align: center; vertical-align: bottom; white-space: nowrap;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt; margin-top: 0pt; margin-left: 0.01pt; text-align: left;">340,000⁽²⁾</div></td><td style="width: 7.27pt;"><div style="font-size: 1pt;"> </div></td><td style="width: 7.27pt;"><div style="font-size: 1pt;"> </div></td><td style="width: 35.17pt; padding-top: 1.01pt; text-align: center; vertical-align: bottom; white-space: nowrap;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt; margin-top: 0pt; margin-left: 3.85pt; text-align: left;">$0.864</div></td><td style="width: 7.27pt;"><div style="font-size: 1pt;"> </div></td><td style="width: 7.27pt;"><div style="font-size: 1pt;"> </div></td><td style="width: 38.87pt; padding-top: 1.01pt; text-align: center; vertical-align: bottom; white-space: nowrap;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt; margin-top: 0pt; margin-left: 0.69pt; text-align: left;">$293,760</div></td><td style="width: 7.27pt;"><div style="font-size: 1pt;"> </div></td><td style="width: 7.27pt;"><div style="font-size: 1pt;"> </div></td><td style="width: 123.67pt; padding-top: 1.01pt; text-align: center; vertical-align: bottom; white-space: nowrap;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt; margin-top: 0pt; margin-left: 59.33pt; text-align: left;">0%</div></td></tr><tr class="BRDSX_boxspacer"><td style="height: 2.75pt; width: 120pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 2.75pt; width: 7.27pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 2.75pt; width: 7.27pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 2.75pt; width: 38.87pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 2.75pt; width: 7.27pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 2.75pt; width: 7.27pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 2.75pt; width: 38.75pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 2.75pt; width: 7.27pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 2.75pt; width: 7.27pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 2.75pt; width: 35.17pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 2.75pt; width: 7.27pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 2.75pt; width: 7.27pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 2.75pt; width: 38.87pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 2.75pt; width: 7.27pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 2.75pt; width: 7.27pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 2.75pt; width: 123.67pt;"><div style="font-size: 1pt;"> </div></td></tr></table><table border="0" cellpadding="0" style="margin-top: 3pt; margin-left: 0pt; border-spacing: 0px;"><tr><td style="width: 20pt; text-align: left; vertical-align: top;"><div style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt;">(1)<br/></div></td><td style="vertical-align: top;"><div style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; text-align: justify;">Represents stock options that vest as to 1/48th of the shares underlying the option on each monthly anniversary of the vesting commencement date, such that 100% of the shares subject to the option will be fully vested and exercisable on the fourth anniversary of the vesting commencement date, subject to the executive’s continued service through each such date.</div></td></tr></table><table border="0" cellpadding="0" style="margin-top: 3pt; margin-left: 0pt; border-spacing: 0px;"><tr><td style="width: 20pt; text-align: left; vertical-align: top;"><div style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt;">(2)<br/></div></td><td style="vertical-align: top;"><div style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; text-align: justify;">Represents stock options that vest as to 1/24th of the shares underlying the option on each monthly anniversary of the vesting commencement date, such that 100% of the shares subject to the option will be fully vested and exercisable on the second anniversary of the vesting commencement date, subject to the executive’s continued service through each such date.</div></td></tr></table><table border="0" cellpadding="0" style="margin-top: 3pt; margin-left: 0pt; border-spacing: 0px;"><tr><td style="width: 20pt; text-align: left; vertical-align: top;"><div style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt;">(3)<br/></div></td><td style="vertical-align: top;"><div style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; text-align: justify;">The amounts reported in this column reflect the grant date fair value of option awards granted to the named executive officers. The grant date fair values have been determined in accordance with FASB ASC Topic 718. For a discussion of the assumptions and methodologies used to calculate these amounts, please see the discussion of option awards contained in the Stock-based Compensation sub-section under Note 13 to our financial statements included in our annual report on Form 10-K for the year ended December 31, 2025. </div></td></tr></table> We generally grant equity awards at regularly scheduled Board of Director or Compensation Committee meetings. true We do not grant equity awards in anticipation of the release of material nonpublic information and we do not time the release of material nonpublic information for the purpose of affecting the value of executive compensation. In the event material nonpublic information becomes known to the Board of Directors or Compensation Committee before granting an equity award, the Board of Directors or Compensation Committee will consider such information and use its business judgment to determine whether to delay the grant of equity to avoid any appearance of impropriety. false true <div class="BRDSX_para" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt; margin-top: 6pt; margin-left: 0pt; text-indent: 20pt; text-align: justify;">The following table sets forth information regarding stock option grants made to the named executive officers during fiscal year 2025 within the period commencing four business days prior to or the one business day following our filing of a Form 8-K on February 3, 2025, that discloses non-public information, as required under Item 4.02(x) of Regulation S-K. We did not view the information in the Form 8-K as material.</div><table cellpadding="0" class="BRDSX_fintab" style="margin-top: 4pt; width: 468pt; margin-left: auto; margin-right: auto; border-spacing: 0px;"><tr class="BRDSX_boxspacer"><td style="height: 6pt; width: 120pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 7.27pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 7.27pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 38.87pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 7.27pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 7.27pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 38.75pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 7.27pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 7.27pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 35.17pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 7.27pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 7.27pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 38.87pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 7.27pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 7.27pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 123.67pt;"><div style="font-size: 1pt;"> </div></td></tr><tr class="BRDSX_header"><td style="width: 120pt; padding-bottom: 2.38pt; text-align: left; vertical-align: bottom; border-bottom: 1pt solid #000000;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; margin-left: 0pt; text-align: left;">Name</div></td><td style="width: 7.27pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 7.27pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 38.87pt; padding-bottom: 2.38pt; text-align: left; vertical-align: bottom; border-bottom: 1pt solid #000000;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; white-space: nowrap; text-align: center;">Grant Date</div></td><td style="width: 7.27pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 7.27pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 38.75pt; padding-bottom: 2.38pt; text-align: left; vertical-align: bottom; border-bottom: 1pt solid #000000;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; white-space: nowrap; text-align: center;">Number of<br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; white-space: nowrap; text-align: center;">Securities<br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; white-space: nowrap; text-align: center;">Underlying<br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; white-space: nowrap; text-align: center;">the Award</div></td><td style="width: 7.27pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 7.27pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 35.17pt; padding-bottom: 2.38pt; text-align: left; vertical-align: bottom; border-bottom: 1pt solid #000000;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; white-space: nowrap; text-align: center;">Exercise <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; white-space: nowrap; text-align: center;">Price of <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; white-space: nowrap; text-align: center;">the Award <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; white-space: nowrap; text-align: center;">($/Sh) </div></td><td style="width: 7.27pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 7.27pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 38.87pt; padding-bottom: 2.38pt; text-align: left; vertical-align: bottom; border-bottom: 1pt solid #000000;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; white-space: nowrap; text-align: center;">Grant Date<br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; white-space: nowrap; text-align: center;">Fair Value<br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; white-space: nowrap; text-align: center;">of the<br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; white-space: nowrap; text-align: center;">Award⁽³⁾</div></td><td style="width: 7.27pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 7.27pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 123.67pt; padding-bottom: 2.38pt; text-align: left; vertical-align: bottom; border-bottom: 1pt solid #000000;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; white-space: nowrap; text-align: center;">Percentage Change in the Closing <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; white-space: nowrap; text-align: center;">Market Price of the Securities <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; white-space: nowrap; text-align: center;">Underlying the Award Between the <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; white-space: nowrap; text-align: center;">Trading Day Ending Immediately <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; white-space: nowrap; text-align: center;">Prior to the Disclosure of MNPI and <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; white-space: nowrap; text-align: center;">the Trading Day Beginning <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; white-space: nowrap; text-align: center;">Immediately Following the <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; white-space: nowrap; text-align: center;">Disclosure of MNPI </div></td></tr><tr><td style="width: 120pt; padding-top: 2.01pt; padding-bottom: 1.38pt; text-align: left; vertical-align: bottom; background-color: #CCEEFF;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt; margin-top: 0pt; margin-left: 0pt; text-align: left;">Sean A. McCarthy, D. Phil</div></td><td style="width: 7.27pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 7.27pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 38.87pt; padding-top: 2.01pt; padding-bottom: 1.38pt; text-align: center; vertical-align: bottom; background-color: #CCEEFF; white-space: nowrap;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt; margin-top: 0pt; margin-left: 1.65pt; text-align: left;">2/5/2025</div></td><td style="width: 7.27pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 7.27pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 38.75pt; padding-top: 2.01pt; padding-bottom: 1.38pt; text-align: center; vertical-align: bottom; background-color: #CCEEFF; white-space: nowrap;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt; margin-top: 0pt; margin-left: 0.01pt; text-align: left;">800,000⁽¹⁾</div></td><td style="width: 7.27pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 7.27pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 35.17pt; padding-top: 2.01pt; padding-bottom: 1.38pt; text-align: center; vertical-align: bottom; background-color: #CCEEFF; white-space: nowrap;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt; margin-top: 0pt; margin-left: 3.85pt; text-align: left;">$0.864</div></td><td style="width: 7.27pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 7.27pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 38.87pt; padding-top: 2.01pt; padding-bottom: 1.38pt; text-align: center; vertical-align: bottom; background-color: #CCEEFF; white-space: nowrap;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt; margin-top: 0pt; margin-left: 0.69pt; text-align: left;">$691,200</div></td><td style="width: 7.27pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 7.27pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 123.67pt; padding-top: 2.01pt; padding-bottom: 1.38pt; text-align: center; vertical-align: bottom; background-color: #CCEEFF; white-space: nowrap;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt; margin-top: 0pt; margin-left: 59.33pt; text-align: left;">0%</div></td></tr><tr><td style="width: 120pt; padding-top: 1.01pt; padding-bottom: 1.38pt; text-align: left; vertical-align: bottom;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt; margin-top: 0pt; margin-left: 0pt; text-align: left;">Sean A. McCarthy, D. Phil</div></td><td style="width: 7.27pt;"><div style="font-size: 1pt;"> </div></td><td style="width: 7.27pt;"><div style="font-size: 1pt;"> </div></td><td style="width: 38.87pt; padding-top: 1.01pt; padding-bottom: 1.38pt; text-align: center; vertical-align: bottom; white-space: nowrap;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt; margin-top: 0pt; margin-left: 1.65pt; text-align: left;">2/5/2025</div></td><td style="width: 7.27pt;"><div style="font-size: 1pt;"> </div></td><td style="width: 7.27pt;"><div style="font-size: 1pt;"> </div></td><td style="width: 38.75pt; padding-top: 1.01pt; padding-bottom: 1.38pt; text-align: center; vertical-align: bottom; white-space: nowrap;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt; margin-top: 0pt; margin-left: 0.01pt; text-align: left;">390,000⁽²⁾</div></td><td style="width: 7.27pt;"><div style="font-size: 1pt;"> </div></td><td style="width: 7.27pt;"><div style="font-size: 1pt;"> </div></td><td style="width: 35.17pt; padding-top: 1.01pt; padding-bottom: 1.38pt; text-align: center; vertical-align: bottom; white-space: nowrap;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt; margin-top: 0pt; margin-left: 3.85pt; text-align: left;">$0.864</div></td><td style="width: 7.27pt;"><div style="font-size: 1pt;"> </div></td><td style="width: 7.27pt;"><div style="font-size: 1pt;"> </div></td><td style="width: 38.87pt; padding-top: 1.01pt; padding-bottom: 1.38pt; text-align: center; vertical-align: bottom; white-space: nowrap;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt; margin-top: 0pt; margin-left: 0.69pt; text-align: left;">$336,960</div></td><td style="width: 7.27pt;"><div style="font-size: 1pt;"> </div></td><td style="width: 7.27pt;"><div style="font-size: 1pt;"> </div></td><td style="width: 123.67pt; padding-top: 1.01pt; padding-bottom: 1.38pt; text-align: center; vertical-align: bottom; white-space: nowrap;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt; margin-top: 0pt; margin-left: 59.33pt; text-align: left;">0%</div></td></tr><tr><td style="width: 120pt; padding-top: 1.01pt; padding-bottom: 1.38pt; text-align: left; vertical-align: bottom; background-color: #CCEEFF;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt; margin-top: 0pt; margin-left: 0pt; text-align: left;">Chris Ogden</div></td><td style="width: 7.27pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 7.27pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 38.87pt; padding-top: 1.01pt; padding-bottom: 1.38pt; text-align: center; vertical-align: bottom; background-color: #CCEEFF; white-space: nowrap;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt; margin-top: 0pt; margin-left: 1.65pt; text-align: left;">2/5/2025</div></td><td style="width: 7.27pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 7.27pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 38.75pt; padding-top: 1.01pt; padding-bottom: 1.38pt; text-align: center; vertical-align: bottom; background-color: #CCEEFF; white-space: nowrap;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt; margin-top: 0pt; margin-left: 0.01pt; text-align: left;">225,000⁽¹⁾</div></td><td style="width: 7.27pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 7.27pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 35.17pt; padding-top: 1.01pt; padding-bottom: 1.38pt; text-align: center; vertical-align: bottom; background-color: #CCEEFF; white-space: nowrap;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt; margin-top: 0pt; margin-left: 3.85pt; text-align: left;">$0.864</div></td><td style="width: 7.27pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 7.27pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 38.87pt; padding-top: 1.01pt; padding-bottom: 1.38pt; text-align: center; vertical-align: bottom; background-color: #CCEEFF; white-space: nowrap;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt; margin-top: 0pt; margin-left: 0.69pt; text-align: left;">$194,400</div></td><td style="width: 7.27pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 7.27pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 123.67pt; padding-top: 1.01pt; padding-bottom: 1.38pt; text-align: center; vertical-align: bottom; background-color: #CCEEFF; white-space: nowrap;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt; margin-top: 0pt; margin-left: 59.33pt; text-align: left;">0%</div></td></tr><tr><td style="width: 120pt; padding-top: 1.01pt; text-align: left; vertical-align: bottom;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt; margin-top: 0pt; margin-left: 0pt; text-align: left;">Chris Ogden</div></td><td style="width: 7.27pt;"><div style="font-size: 1pt;"> </div></td><td style="width: 7.27pt;"><div style="font-size: 1pt;"> </div></td><td style="width: 38.87pt; padding-top: 1.01pt; text-align: center; vertical-align: bottom; white-space: nowrap;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt; margin-top: 0pt; margin-left: 1.65pt; text-align: left;">2/5/2025</div></td><td style="width: 7.27pt;"><div style="font-size: 1pt;"> </div></td><td style="width: 7.27pt;"><div style="font-size: 1pt;"> </div></td><td style="width: 38.75pt; padding-top: 1.01pt; text-align: center; vertical-align: bottom; white-space: nowrap;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt; margin-top: 0pt; margin-left: 0.01pt; text-align: left;">340,000⁽²⁾</div></td><td style="width: 7.27pt;"><div style="font-size: 1pt;"> </div></td><td style="width: 7.27pt;"><div style="font-size: 1pt;"> </div></td><td style="width: 35.17pt; padding-top: 1.01pt; text-align: center; vertical-align: bottom; white-space: nowrap;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt; margin-top: 0pt; margin-left: 3.85pt; text-align: left;">$0.864</div></td><td style="width: 7.27pt;"><div style="font-size: 1pt;"> </div></td><td style="width: 7.27pt;"><div style="font-size: 1pt;"> </div></td><td style="width: 38.87pt; padding-top: 1.01pt; text-align: center; vertical-align: bottom; white-space: nowrap;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt; margin-top: 0pt; margin-left: 0.69pt; text-align: left;">$293,760</div></td><td style="width: 7.27pt;"><div style="font-size: 1pt;"> </div></td><td style="width: 7.27pt;"><div style="font-size: 1pt;"> </div></td><td style="width: 123.67pt; padding-top: 1.01pt; text-align: center; vertical-align: bottom; white-space: nowrap;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt; margin-top: 0pt; margin-left: 59.33pt; text-align: left;">0%</div></td></tr><tr class="BRDSX_boxspacer"><td style="height: 2.75pt; width: 120pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 2.75pt; width: 7.27pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 2.75pt; width: 7.27pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 2.75pt; width: 38.87pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 2.75pt; width: 7.27pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 2.75pt; width: 7.27pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 2.75pt; width: 38.75pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 2.75pt; width: 7.27pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 2.75pt; width: 7.27pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 2.75pt; width: 35.17pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 2.75pt; width: 7.27pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 2.75pt; width: 7.27pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 2.75pt; width: 38.87pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 2.75pt; width: 7.27pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 2.75pt; width: 7.27pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 2.75pt; width: 123.67pt;"><div style="font-size: 1pt;"> </div></td></tr></table><table border="0" cellpadding="0" style="margin-top: 3pt; margin-left: 0pt; border-spacing: 0px;"><tr><td style="width: 20pt; text-align: left; vertical-align: top;"><div style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt;">(1)<br/></div></td><td style="vertical-align: top;"><div style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; text-align: justify;">Represents stock options that vest as to 1/48th of the shares underlying the option on each monthly anniversary of the vesting commencement date, such that 100% of the shares subject to the option will be fully vested and exercisable on the fourth anniversary of the vesting commencement date, subject to the executive’s continued service through each such date.</div></td></tr></table><table border="0" cellpadding="0" style="margin-top: 3pt; margin-left: 0pt; border-spacing: 0px;"><tr><td style="width: 20pt; text-align: left; vertical-align: top;"><div style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt;">(2)<br/></div></td><td style="vertical-align: top;"><div style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; text-align: justify;">Represents stock options that vest as to 1/24th of the shares underlying the option on each monthly anniversary of the vesting commencement date, such that 100% of the shares subject to the option will be fully vested and exercisable on the second anniversary of the vesting commencement date, subject to the executive’s continued service through each such date.</div></td></tr></table><table border="0" cellpadding="0" style="margin-top: 3pt; margin-left: 0pt; border-spacing: 0px;"><tr><td style="width: 20pt; text-align: left; vertical-align: top;"><div style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt;">(3)<br/></div></td><td style="vertical-align: top;"><div style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; text-align: justify;">The amounts reported in this column reflect the grant date fair value of option awards granted to the named executive officers. The grant date fair values have been determined in accordance with FASB ASC Topic 718. For a discussion of the assumptions and methodologies used to calculate these amounts, please see the discussion of option awards contained in the Stock-based Compensation sub-section under Note 13 to our financial statements included in our annual report on Form 10-K for the year ended December 31, 2025. </div></td></tr></table> Sean A. McCarthy, D. Phil 800000 0.864 691200 0 Sean A. McCarthy, D. Phil 390000 0.864 336960 0 Chris Ogden 225000 0.864 194400 0 Chris Ogden 340000 0.864 293760 0 <div class="BRDSX_h1" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt; font-weight: bold; margin-top: 6.75pt; text-align: center;">PAY VERSUS PERFORMANCE </div><div class="BRDSX_para" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt; margin-top: 6pt; margin-left: 0pt; text-indent: 20pt; text-align: justify;">In accordance with rules adopted by the Securities and Exchange Commission pursuant to the Dodd-Frank Wall Street Reform and Consumer Protection Act of 2010, we provide the following disclosure regarding executive compensation for our principal executive officer (“PEO”) and Non-PEO NEOs and Company performance for the fiscal years listed below. The Compensation Committee did not consider the pay versus performance disclosure below in making its pay decisions for any of the years shown. </div><table cellpadding="0" class="BRDSX_fintab" style="width: 468pt; margin-left: auto; margin-right: auto; border-spacing: 0px;"><tr class="BRDSX_boxspacer"><td style="height: 6pt; width: 132pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 3.79pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 3.79pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 51.01pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 3.79pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 3.79pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 49.32pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 3.79pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 3.79pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 50.38pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 3.79pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 3.79pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 49.32pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 3.79pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 3.79pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 42pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 3.79pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 3.79pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 48.52pt;"><div style="font-size: 1pt;"> </div></td></tr><tr class="BRDSX_header"><td style="width: 132pt; padding-bottom: 2.38pt; text-align: left; vertical-align: bottom; border-bottom: 1pt solid #000000;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; margin-left: 0pt; text-align: left;">Year</div></td><td style="width: 3.79pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 3.79pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 51.01pt; padding-bottom: 2.38pt; text-align: left; vertical-align: bottom; border-bottom: 1pt solid #000000;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; white-space: nowrap; text-align: center;">Summary <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; white-space: nowrap; text-align: center;">Compensation <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; white-space: nowrap; text-align: center;">Table <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; white-space: nowrap; text-align: center;">Total for PEO¹ <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; white-space: nowrap; text-align: center;">($)</div></td><td style="width: 3.79pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 3.79pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 49.32pt; padding-bottom: 2.38pt; text-align: left; vertical-align: bottom; border-bottom: 1pt solid #000000;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; white-space: nowrap; text-align: center;">Compensation <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; white-space: nowrap; text-align: center;">Actually Paid <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; white-space: nowrap; text-align: center;">to PEO^1,2,3<br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; white-space: nowrap; text-align: center;">($)</div></td><td style="width: 3.79pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 3.79pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 50.38pt; padding-bottom: 2.38pt; text-align: left; vertical-align: bottom; border-bottom: 1pt solid #000000;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; white-space: nowrap; text-align: center;">Average <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; white-space: nowrap; text-align: center;">Summary <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; white-space: nowrap; text-align: center;">Compensation <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; white-space: nowrap; text-align: center;">Table Total for <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; white-space: nowrap; text-align: center;">Non-PEO <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; white-space: nowrap; text-align: center;">NEOs¹ <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; white-space: nowrap; text-align: center;">($)</div></td><td style="width: 3.79pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 3.79pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 49.32pt; padding-bottom: 2.38pt; text-align: left; vertical-align: bottom; border-bottom: 1pt solid #000000;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; white-space: nowrap; text-align: center;">Average <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; white-space: nowrap; text-align: center;">Compensation <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; white-space: nowrap; text-align: center;">Actually Paid <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; white-space: nowrap; text-align: center;">to Non-PEO <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; white-space: nowrap; text-align: center;">NEOs^1,2,3 <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; white-space: nowrap; text-align: center;">($)</div></td><td style="width: 3.79pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 3.79pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 42pt; padding-bottom: 2.38pt; text-align: left; vertical-align: bottom; border-bottom: 1pt solid #000000;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; white-space: nowrap; text-align: center;">Value of <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; white-space: nowrap; text-align: center;">Initial Fixed <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; white-space: nowrap; text-align: center;">$100 <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; white-space: nowrap; text-align: center;">Investment <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; white-space: nowrap; text-align: center;">based on <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; white-space: nowrap; text-align: center;">TSR⁴</div></td><td style="width: 3.79pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 3.79pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 48.52pt; padding-bottom: 2.38pt; text-align: left; vertical-align: bottom; border-bottom: 1pt solid #000000;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; white-space: nowrap; text-align: center;">Net Income<br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; white-space: nowrap; text-align: center;">($ Thousands) </div></td></tr><tr><td style="width: 132pt; padding-top: 2.01pt; padding-bottom: 1.38pt; text-align: left; vertical-align: bottom; background-color: #CCEEFF;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt; font-weight: bold; margin-top: 0pt; margin-left: 0pt; text-align: left;">2025</div></td><td style="width: 3.79pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 3.79pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 51.01pt; padding-top: 2.01pt; padding-bottom: 1.38pt; text-align: center; vertical-align: bottom; background-color: #CCEEFF; white-space: nowrap;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt; font-weight: bold; margin-top: 0pt; margin-left: 5.5pt; text-align: left;">4,738,494</div></td><td style="width: 3.79pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 3.79pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 49.32pt; padding-top: 2.01pt; padding-bottom: 1.38pt; text-align: center; vertical-align: bottom; background-color: #CCEEFF; white-space: nowrap;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt; font-weight: bold; margin-top: 0pt; margin-left: 2.16pt; text-align: left;">10,636,158</div></td><td style="width: 3.79pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 3.79pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 50.38pt; padding-top: 2.01pt; padding-bottom: 1.38pt; text-align: center; vertical-align: bottom; background-color: #CCEEFF; white-space: nowrap;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt; font-weight: bold; margin-top: 0pt; margin-left: 5.18pt; text-align: left;">1,888,753</div></td><td style="width: 3.79pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 3.79pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 49.32pt; padding-top: 2.01pt; padding-bottom: 1.38pt; text-align: center; vertical-align: bottom; background-color: #CCEEFF; white-space: nowrap;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt; font-weight: bold; margin-top: 0pt; margin-left: 4.66pt; text-align: left;">2,948,461</div></td><td style="width: 3.79pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 3.79pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 42pt; padding-top: 2.01pt; padding-bottom: 1.38pt; text-align: center; vertical-align: bottom; background-color: #CCEEFF; white-space: nowrap;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt; font-weight: bold; margin-top: 0pt; margin-left: 7.25pt; text-align: left;">266.25 </div></td><td style="width: 3.79pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 3.79pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 48.52pt; padding-top: 2.01pt; padding-bottom: 1.38pt; text-align: center; vertical-align: bottom; background-color: #CCEEFF; white-space: nowrap;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt; font-weight: bold; margin-top: 0pt; margin-left: 8.85pt; text-align: left;">(20,370) </div></td></tr><tr><td style="width: 132pt; padding-top: 1.01pt; padding-bottom: 1.38pt; text-align: left; vertical-align: bottom;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt; font-weight: bold; margin-top: 0pt; margin-left: 0pt; text-align: left;">2024</div></td><td style="width: 3.79pt;"><div style="font-size: 1pt;"> </div></td><td style="width: 3.79pt;"><div style="font-size: 1pt;"> </div></td><td style="width: 51.01pt; padding-top: 1.01pt; padding-bottom: 1.38pt; text-align: center; vertical-align: bottom; white-space: nowrap;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt; font-weight: bold; margin-top: 0pt; margin-left: 5.5pt; text-align: left;">1,752,802 </div></td><td style="width: 3.79pt;"><div style="font-size: 1pt;"> </div></td><td style="width: 3.79pt;"><div style="font-size: 1pt;"> </div></td><td style="width: 49.32pt; padding-top: 1.01pt; padding-bottom: 1.38pt; text-align: center; vertical-align: bottom; white-space: nowrap;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt; font-weight: bold; margin-top: 0pt; margin-left: 2.16pt; text-align: left;"><span style="padding-left: 5pt;">1,063,510 </span></div></td><td style="width: 3.79pt;"><div style="font-size: 1pt;"> </div></td><td style="width: 3.79pt;"><div style="font-size: 1pt;"> </div></td><td style="width: 50.38pt; padding-top: 1.01pt; padding-bottom: 1.38pt; text-align: center; vertical-align: bottom; white-space: nowrap;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt; font-weight: bold; margin-top: 0pt; margin-left: 5.18pt; text-align: left;"><span style="padding-left: 7.5pt;">861,316 </span></div></td><td style="width: 3.79pt;"><div style="font-size: 1pt;"> </div></td><td style="width: 3.79pt;"><div style="font-size: 1pt;"> </div></td><td style="width: 49.32pt; padding-top: 1.01pt; padding-bottom: 1.38pt; text-align: center; vertical-align: bottom; white-space: nowrap;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt; font-weight: bold; margin-top: 0pt; margin-left: 4.66pt; text-align: left;"><span style="padding-left: 8.05pt;">611,437 </span></div></td><td style="width: 3.79pt;"><div style="font-size: 1pt;"> </div></td><td style="width: 3.79pt;"><div style="font-size: 1pt;"> </div></td><td style="width: 42pt; padding-top: 1.01pt; padding-bottom: 1.38pt; text-align: center; vertical-align: bottom; white-space: nowrap;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt; font-weight: bold; margin-top: 0pt; margin-left: 7.25pt; text-align: left;"><span style="padding-left: 5pt;">64.38 </span></div></td><td style="width: 3.79pt;"><div style="font-size: 1pt;"> </div></td><td style="width: 3.79pt;"><div style="font-size: 1pt;"> </div></td><td style="width: 48.52pt; padding-top: 1.01pt; padding-bottom: 1.38pt; text-align: center; vertical-align: bottom; white-space: nowrap;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt; font-weight: bold; margin-top: 0pt; margin-left: 8.85pt; text-align: left;"><span style="padding-left: 3.33pt;">31,869 </span></div></td></tr><tr><td style="width: 132pt; padding-top: 1.01pt; text-align: left; vertical-align: bottom; background-color: #CCEEFF;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt; font-weight: bold; margin-top: 0pt; margin-left: 0pt; text-align: left;">2023</div></td><td style="width: 3.79pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 3.79pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 51.01pt; padding-top: 1.01pt; text-align: center; vertical-align: bottom; background-color: #CCEEFF; white-space: nowrap;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt; font-weight: bold; margin-top: 0pt; margin-left: 5.5pt; text-align: left;"><span style="padding-left: 0.55pt;">2,611,138 </span></div></td><td style="width: 3.79pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 3.79pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 49.32pt; padding-top: 1.01pt; text-align: center; vertical-align: bottom; background-color: #CCEEFF; white-space: nowrap;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt; font-weight: bold; margin-top: 0pt; margin-left: 2.16pt; text-align: left;"><span style="padding-left: 12.5pt;">519,365 </span></div></td><td style="width: 3.79pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 3.79pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 50.38pt; padding-top: 1.01pt; text-align: center; vertical-align: bottom; background-color: #CCEEFF; white-space: nowrap;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt; font-weight: bold; margin-top: 0pt; margin-left: 5.18pt; text-align: left;">1,127,080 </div></td><td style="width: 3.79pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 3.79pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 49.32pt; padding-top: 1.01pt; text-align: center; vertical-align: bottom; background-color: #CCEEFF; white-space: nowrap;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt; font-weight: bold; margin-top: 0pt; margin-left: 4.66pt; text-align: left;"><span style="padding-left: 7.5pt;">528,064 </span></div></td><td style="width: 3.79pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 3.79pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 42pt; padding-top: 1.01pt; text-align: center; vertical-align: bottom; background-color: #CCEEFF; white-space: nowrap;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt; font-weight: bold; margin-top: 0pt; margin-left: 7.25pt; text-align: left;"><span style="padding-left: 5pt;">96.88 </span></div></td><td style="width: 3.79pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 3.79pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 48.52pt; padding-top: 1.01pt; text-align: center; vertical-align: bottom; background-color: #CCEEFF; white-space: nowrap;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt; font-weight: bold; margin-top: 0pt; margin-left: 8.85pt; text-align: left;"><span style="padding-left: 12.5pt;">(569)</span></div></td></tr><tr class="BRDSX_boxspacer"><td style="height: 2.75pt; width: 132pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 2.75pt; width: 3.79pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 2.75pt; width: 3.79pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 2.75pt; width: 51.01pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 2.75pt; width: 3.79pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 2.75pt; width: 3.79pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 2.75pt; width: 49.32pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 2.75pt; width: 3.79pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 2.75pt; width: 3.79pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 2.75pt; width: 50.38pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 2.75pt; width: 3.79pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 2.75pt; width: 3.79pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 2.75pt; width: 49.32pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 2.75pt; width: 3.79pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 2.75pt; width: 3.79pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 2.75pt; width: 42pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 2.75pt; width: 3.79pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 2.75pt; width: 3.79pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 2.75pt; width: 48.52pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td></tr></table><table border="0" cellpadding="0" style="margin-top: 3pt; margin-left: 0pt; border-spacing: 0px;"><tr><td style="width: 20pt; text-align: left; vertical-align: top;"><div style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt;">1.<br/></div></td><td style="vertical-align: top;"><div style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; text-align: justify;">Sean A. McCarthy, D. Phil. was our PEO for each year presented. The individuals comprising the Non-PEO NEOs for each year presented are listed below. </div></td></tr></table><table cellpadding="0" class="BRDSX_txttab" style="width: 448pt; margin-left: 20pt; border-spacing: 0px;"><tr class="BRDSX_boxspacer"><td style="height: 6pt; width: 141.34pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 6pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 6pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 141.33pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 6pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 6pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 141.33pt;"><div style="font-size: 1pt;"> </div></td></tr><tr class="BRDSX_header"><td style="width: 141.34pt; padding-bottom: 2.38pt; text-align: left; vertical-align: bottom; border-bottom: 1pt solid #000000;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">2023</div></td><td style="width: 6pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 6pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 141.33pt; padding-bottom: 2.38pt; text-align: left; vertical-align: bottom; border-bottom: 1pt solid #000000;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">2024</div></td><td style="width: 6pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 6pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 141.33pt; padding-bottom: 2.38pt; text-align: left; vertical-align: bottom; border-bottom: 1pt solid #000000;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">2025 </div></td></tr><tr><td style="width: 141.34pt; padding-top: 2.08pt; padding-bottom: 1.63pt; text-align: left; vertical-align: top;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; margin-top: 0pt; text-align: center;">Jeff Landau</div></td><td style="width: 6pt;"><div style="font-size: 1pt;"> </div></td><td style="width: 6pt;"><div style="font-size: 1pt;"> </div></td><td style="width: 141.33pt; padding-top: 2.08pt; padding-bottom: 1.63pt; text-align: left; vertical-align: bottom;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; margin-top: 0pt; text-align: center;">Chris Ogden</div></td><td style="width: 6pt;"><div style="font-size: 1pt;"> </div></td><td style="width: 6pt;"><div style="font-size: 1pt;"> </div></td><td style="width: 141.33pt; padding-top: 2.08pt; padding-bottom: 1.63pt; text-align: left; vertical-align: bottom;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; margin-top: 0pt; text-align: center;">Chris Ogden </div></td></tr><tr><td style="width: 141.34pt; padding-top: 1.33pt; text-align: left; vertical-align: top;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; margin-top: 0pt; text-align: center;">Marcia P. Belvin</div></td><td style="width: 6pt;"><div style="font-size: 1pt;"> </div></td><td style="width: 6pt;"><div style="font-size: 1pt;"> </div></td><td style="width: 141.33pt; padding-top: 1.33pt; text-align: left; vertical-align: bottom;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; margin-top: 0pt; text-align: center;">Wayne Chu</div></td><td style="width: 6pt;"><div style="font-size: 1pt;"> </div></td><td style="width: 6pt;"><div style="font-size: 1pt;"> </div></td><td style="width: 141.33pt; padding-top: 1.33pt; text-align: left; vertical-align: bottom;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; margin-top: 0pt; text-align: center;">Rachael Lester</div></td></tr><tr class="BRDSX_boxspacer"><td style="height: 3.25pt; width: 141.34pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 6pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 6pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 141.33pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 6pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 6pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 141.33pt;"><div style="font-size: 1pt;"> </div></td></tr></table><table border="0" cellpadding="0" style="margin-top: 3pt; margin-left: 0pt; border-spacing: 0px;"><tr><td style="width: 20pt; text-align: left; vertical-align: top;"><div style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt;">2.<br/></div></td><td style="vertical-align: top;"><div style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; text-align: justify;">The amounts shown for Compensation Actually Paid have been calculated in accordance with Item 402(v) of Regulation S-K and do not reflect compensation actually earned, realized, or received by the Company’s NEOs. These amounts reflect the Summary Compensation Table Total with certain adjustments as described in footnote 3 below. </div></td></tr></table><table border="0" cellpadding="0" style="margin-top: 3pt; margin-left: 0pt; border-spacing: 0px;"><tr><td style="width: 20pt; text-align: left; vertical-align: top;"><div style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt;">3.<br/></div></td><td style="vertical-align: top;"><div style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; text-align: justify;">Compensation Actually Paid reflects the exclusions and inclusions of certain amounts for the PEO and the Non-PEO NEOs as set forth below. Equity values are calculated in accordance with FASB ASC Topic 718. Amounts in the Exclusion of Stock Awards and Option Awards column are the totals from the Stock Awards and Option Awards columns set forth in the Summary Compensation Table. </div></td></tr></table><table cellpadding="0" class="BRDSX_fintab" style="margin-top: 4pt; width: 448pt; margin-left: 20pt; border-spacing: 0px;"><tr class="BRDSX_boxspacer"><td style="height: 6pt; width: 216pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 4.76pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 4.76pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 50.38pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 4.76pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 4.76pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 46.87pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 4.76pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 4.76pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 47.34pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 4.76pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 4.76pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 49.32pt;"><div style="font-size: 1pt;"> </div></td></tr><tr class="BRDSX_header"><td style="width: 216pt; padding-bottom: 2.38pt; text-align: left; vertical-align: bottom; border-bottom: 1pt solid #000000;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; margin-left: 0pt; text-align: left;">Year</div></td><td style="width: 4.76pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 4.76pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 50.38pt; padding-bottom: 2.38pt; text-align: left; vertical-align: bottom; border-bottom: 1pt solid #000000;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Summary <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Compensation <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Table Total for <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Sean <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">A. McCarthy, <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">D. Phil. <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">($)</div></td><td style="width: 4.76pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 4.76pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 46.87pt; padding-bottom: 2.38pt; text-align: left; vertical-align: bottom; border-bottom: 1pt solid #000000;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Exclusion of <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Stock Awards <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">and Option <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Awards for <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Sean <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">A. McCarthy, <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">D. Phil. <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">($)</div></td><td style="width: 4.76pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 4.76pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 47.34pt; padding-bottom: 2.38pt; text-align: left; vertical-align: bottom; border-bottom: 1pt solid #000000;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Inclusion of <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Equity Values <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">for Sean <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">A. McCarthy, <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">D. Phil. <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">($)</div></td><td style="width: 4.76pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 4.76pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 49.32pt; padding-bottom: 2.38pt; text-align: left; vertical-align: bottom; border-bottom: 1pt solid #000000;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Compensation <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Actually Paid <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">to Sean <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">A. McCarthy, <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">D. Phil. <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">($) </div></td></tr><tr><td style="width: 216pt; padding-top: 2.08pt; text-align: left; vertical-align: bottom; background-color: #CCEEFF;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; margin-top: 0pt; margin-left: 0pt; text-align: left;">2025</div></td><td style="width: 4.76pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 4.76pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 50.38pt; padding-top: 2.08pt; text-align: center; vertical-align: bottom; background-color: #CCEEFF; white-space: nowrap;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; margin-top: 0pt; margin-left: 9.19pt; text-align: left;">4,738,494</div></td><td style="width: 4.76pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 4.76pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 46.87pt; padding-top: 2.08pt; text-align: center; vertical-align: bottom; background-color: #CCEEFF; white-space: nowrap;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; margin-top: 0pt; margin-left: 6.11pt; text-align: left;">(3,308,633)</div></td><td style="width: 4.76pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 4.76pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 47.34pt; padding-top: 2.08pt; text-align: center; vertical-align: bottom; background-color: #CCEEFF; white-space: nowrap;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; margin-top: 0pt; margin-left: 7.68pt; text-align: left;">9,206,297</div></td><td style="width: 4.76pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 4.76pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 49.32pt; padding-top: 2.08pt; text-align: center; vertical-align: bottom; background-color: #CCEEFF; white-space: nowrap;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; margin-top: 0pt; margin-left: 6.66pt; text-align: left;">10,636,158</div></td></tr><tr class="BRDSX_boxspacer"><td style="height: 3.25pt; width: 216pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 4.76pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 4.76pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 50.38pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 4.76pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 4.76pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 46.87pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 4.76pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 4.76pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 47.34pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 4.76pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 4.76pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 49.32pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td></tr></table><table cellpadding="0" class="BRDSX_fintab" style="width: 448pt; margin-left: 20pt; border-spacing: 0px;"><tr class="BRDSX_boxspacer"><td style="height: 6pt; width: 216pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 4.78pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 4.78pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 50.38pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 4.78pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 4.78pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 46.73pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 4.78pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 4.78pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 47.34pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 4.78pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 4.78pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 49.32pt;"><div style="font-size: 1pt;"> </div></td></tr><tr class="BRDSX_header"><td style="width: 216pt; padding-bottom: 2.38pt; text-align: left; vertical-align: bottom; border-bottom: 1pt solid #000000;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; margin-left: 0pt; text-align: left;">Year</div></td><td style="width: 4.78pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 4.78pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 50.38pt; padding-bottom: 2.38pt; text-align: left; vertical-align: bottom; border-bottom: 1pt solid #000000;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Average <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Summary <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Compensation <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Table Total for <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Non-PEO <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">NEOs <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">($)</div></td><td style="width: 4.78pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 4.78pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 46.73pt; padding-bottom: 2.38pt; text-align: left; vertical-align: bottom; border-bottom: 1pt solid #000000;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Average <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Exclusion of <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Stock Awards <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">and Option <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Awards for <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Non-PEO <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">NEOs<br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">($)</div></td><td style="width: 4.78pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 4.78pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 47.34pt; padding-bottom: 2.38pt; text-align: left; vertical-align: bottom; border-bottom: 1pt solid #000000;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Average <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Inclusion of <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Equity Values <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">for Non-PEO <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">NEOs <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">($)</div></td><td style="width: 4.78pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 4.78pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 49.32pt; padding-bottom: 2.38pt; text-align: left; vertical-align: bottom; border-bottom: 1pt solid #000000;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Average <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Compensation <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Actually Paid <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">to Non-PEO <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">NEOs <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">($) </div></td></tr><tr><td style="width: 216pt; padding-top: 2.08pt; text-align: left; vertical-align: bottom; background-color: #CCEEFF;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; margin-top: 0pt; margin-left: 0pt; text-align: left;">2025</div></td><td style="width: 4.78pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 4.78pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 50.38pt; padding-top: 2.08pt; text-align: center; vertical-align: bottom; background-color: #CCEEFF; white-space: nowrap;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; margin-top: 0pt; margin-left: 9.19pt; text-align: left;">1,888,753</div></td><td style="width: 4.78pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 4.78pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 46.73pt; padding-top: 2.08pt; text-align: center; vertical-align: bottom; background-color: #CCEEFF; white-space: nowrap;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; margin-top: 0pt; margin-left: 6.03pt; text-align: left;">(1,332,326)</div></td><td style="width: 4.78pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 4.78pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 47.34pt; padding-top: 2.08pt; text-align: center; vertical-align: bottom; background-color: #CCEEFF; white-space: nowrap;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; margin-top: 0pt; margin-left: 7.67pt; text-align: left;">2,392,034</div></td><td style="width: 4.78pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 4.78pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 49.32pt; padding-top: 2.08pt; text-align: center; vertical-align: bottom; background-color: #CCEEFF; white-space: nowrap;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; margin-top: 0pt; margin-left: 8.66pt; text-align: left;">2,948,461</div></td></tr><tr class="BRDSX_boxspacer"><td style="height: 3.25pt; width: 216pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 4.78pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 4.78pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 50.38pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 4.78pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 4.78pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 46.73pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 4.78pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 4.78pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 47.34pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 4.78pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 4.78pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 49.32pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td></tr></table><div class="BRDSX_ftnote" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; margin-top: 5.25pt; margin-left: 20pt; text-align: left;">The amounts in the Inclusion of Equity Values in the tables above are derived from the amounts set forth in the following tables: </div><table cellpadding="0" class="BRDSX_fintab" style="width: 448pt; margin-left: 20pt; border-spacing: 0px;"><tr class="BRDSX_boxspacer"><td style="height: 6pt; width: 120pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 3.79pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 3.79pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 46.87pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 3.79pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 3.79pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 46.87pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 3.79pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 3.79pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 46.87pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 3.79pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 3.79pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 46.87pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 3.79pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 3.79pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 48.2pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 3.79pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 3.79pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 46.87pt;"><div style="font-size: 1pt;"> </div></td></tr><tr class="BRDSX_header"><td style="width: 120pt; padding-bottom: 2.38pt; text-align: left; vertical-align: bottom; border-bottom: 1pt solid #000000;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; margin-left: 0pt; text-align: left;">Year</div></td><td style="width: 3.79pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 3.79pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 46.87pt; padding-bottom: 2.38pt; text-align: left; vertical-align: bottom; border-bottom: 1pt solid #000000;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Year-End <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Fair Value of <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Equity <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Awards <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Granted <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">During Year <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">That <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Remained <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Unvested as <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">of Last Day <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">of Year for <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Sean <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">A. McCarthy, <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">D. Phil. <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">($)</div></td><td style="width: 3.79pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 3.79pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 46.87pt; padding-bottom: 2.38pt; text-align: left; vertical-align: bottom; border-bottom: 1pt solid #000000;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Change in <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Fair Value <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">from Last <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Day of Prior <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Year to Last <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Day of Year <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">of Unvested <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Equity <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Awards for <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Sean <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">A. McCarthy, <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">D. Phil. <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">($)</div></td><td style="width: 3.79pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 3.79pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 46.87pt; padding-bottom: 2.38pt; text-align: left; vertical-align: bottom; border-bottom: 1pt solid #000000;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Vesting-Date <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Fair Value of <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Equity <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Awards <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Granted <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">During Year <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">that Vested <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">During Year <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">for Sean <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">A. McCarthy, <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">D. Phil. <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">($)</div></td><td style="width: 3.79pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 3.79pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 46.87pt; padding-bottom: 2.38pt; text-align: left; vertical-align: bottom; border-bottom: 1pt solid #000000;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Change in <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Fair Value <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">from Last <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Day of Prior <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Year to <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Vesting Date <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">of Unvested <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Equity <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Awards that <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Vested <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">During Year <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">for Sean <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">A. McCarthy, <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">D. Phil. <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">($)</div></td><td style="width: 3.79pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 3.79pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 48.2pt; padding-bottom: 2.38pt; text-align: left; vertical-align: bottom; border-bottom: 1pt solid #000000;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Fair Value <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">at Last Day of <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Prior Year <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">of Equity <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Awards <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Forfeited <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">During Year <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">for Sean <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">A. McCarthy, <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">D. Phil. <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">($)</div></td><td style="width: 3.79pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 3.79pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 46.87pt; padding-bottom: 2.38pt; text-align: left; vertical-align: bottom; border-bottom: 1pt solid #000000;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Total - <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Inclusion of<br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Equity <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Values for <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Sean <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">A. McCarthy, <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">D. Phil. <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">($) </div></td></tr><tr><td style="width: 120pt; padding-top: 2.08pt; text-align: left; vertical-align: bottom; background-color: #CCEEFF;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; margin-top: 0pt; margin-left: 0pt; text-align: left;">2025</div></td><td style="width: 3.79pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 3.79pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 46.87pt; padding-top: 2.08pt; text-align: center; vertical-align: bottom; background-color: #CCEEFF; white-space: nowrap;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; margin-top: 0pt; margin-left: 7.43pt; text-align: left;">6,876,499 </div></td><td style="width: 3.79pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 3.79pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 46.87pt; padding-top: 2.08pt; text-align: center; vertical-align: bottom; background-color: #CCEEFF; white-space: nowrap;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; margin-top: 0pt; margin-left: 7.43pt; text-align: left;">1,302,775 </div></td><td style="width: 3.79pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 3.79pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 46.87pt; padding-top: 2.08pt; text-align: center; vertical-align: bottom; background-color: #CCEEFF; white-space: nowrap;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; margin-top: 0pt; margin-left: 10.44pt; text-align: left;">780,454 </div></td><td style="width: 3.79pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 3.79pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 46.87pt; padding-top: 2.08pt; text-align: center; vertical-align: bottom; background-color: #CCEEFF; white-space: nowrap;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; margin-top: 0pt; margin-left: 10.44pt; text-align: left;">246,569 </div></td><td style="width: 3.79pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 3.79pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 48.2pt; padding-top: 2.08pt; text-align: center; vertical-align: bottom; background-color: #CCEEFF; white-space: nowrap;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; margin-top: 0pt; margin-left: 20.1pt; text-align: left;">—</div></td><td style="width: 3.79pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 3.79pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 46.87pt; padding-top: 2.08pt; text-align: center; vertical-align: bottom; background-color: #CCEEFF; white-space: nowrap;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; margin-top: 0pt; margin-left: 7.45pt; text-align: left;">9,206,297</div></td></tr><tr class="BRDSX_boxspacer"><td style="height: 3.25pt; width: 120pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 3.79pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 3.79pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 46.87pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 3.79pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 3.79pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 46.87pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 3.79pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 3.79pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 46.87pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 3.79pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 3.79pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 46.87pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 3.79pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 3.79pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 48.2pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 3.79pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 3.79pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 46.87pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td></tr></table><table cellpadding="0" class="BRDSX_fintab" style="width: 448pt; margin-left: 20pt; border-spacing: 0px;"><tr class="BRDSX_boxspacer"><td style="height: 6pt; width: 96pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 4.1pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 4.1pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 51.87pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 4.1pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 4.1pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 51.55pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 4.1pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 4.1pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 50.74pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 4.1pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 4.1pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 51.68pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 4.1pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 4.1pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 49.62pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 4.1pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 4.1pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 47.34pt;"><div style="font-size: 1pt;"> </div></td></tr><tr class="BRDSX_header"><td style="width: 96pt; padding-bottom: 2.38pt; text-align: left; vertical-align: bottom; border-bottom: 1pt solid #000000;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; margin-left: 0pt; text-align: left;">Year</div></td><td style="width: 4.1pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 4.1pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 51.87pt; padding-bottom: 2.38pt; text-align: left; vertical-align: bottom; border-bottom: 1pt solid #000000;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Average Year-<br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">End Fair Value <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">of Equity <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Awards <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Granted <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">During Year <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">That <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Remained <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Unvested as of <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Last Day of <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Year for Non-<br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">PEO NEOs <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">($)</div></td><td style="width: 4.1pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 4.1pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 51.55pt; padding-bottom: 2.38pt; text-align: left; vertical-align: bottom; border-bottom: 1pt solid #000000;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Average <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Change in Fair <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Value from <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Last Day of <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Prior Year to <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Last Day of <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Year of <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Unvested <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Equity Awards <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">for Non-PEO <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">NEOs <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">($)</div></td><td style="width: 4.1pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 4.1pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 50.74pt; padding-bottom: 2.38pt; text-align: left; vertical-align: bottom; border-bottom: 1pt solid #000000;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Average <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Vesting-Date <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Fair Value of <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Equity Awards <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Granted <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">During Year <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">that Vested <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">During Year <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">for Non-PEO <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">NEOs <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">($)</div></td><td style="width: 4.1pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 4.1pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 51.68pt; padding-bottom: 2.38pt; text-align: left; vertical-align: bottom; border-bottom: 1pt solid #000000;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Average <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Change in Fair <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Value from <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Last Day of <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Prior Year to <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Vesting Date of <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Unvested <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Equity Awards <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">that Vested <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">During Year <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">for Non-PEO <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">NEOs <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">($)</div></td><td style="width: 4.1pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 4.1pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 49.62pt; padding-bottom: 2.38pt; text-align: left; vertical-align: bottom; border-bottom: 1pt solid #000000;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Average Fair <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Value at Last <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Day of Prior <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Year of Equity <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Awards <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Forfeited <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">During Year <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">for Non-PEO <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">NEOs <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">($)</div></td><td style="width: 4.1pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 4.1pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 47.34pt; padding-bottom: 2.38pt; text-align: left; vertical-align: bottom; border-bottom: 1pt solid #000000;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Total - <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Average <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Inclusion of<br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Equity Values <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">for Non-PEO <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">NEOs<br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">($) </div></td></tr><tr><td style="width: 96pt; padding-top: 2.08pt; text-align: left; vertical-align: bottom; background-color: #CCEEFF;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; margin-top: 0pt; margin-left: 0pt; text-align: left;">2025</div></td><td style="width: 4.1pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 4.1pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 51.87pt; padding-top: 2.08pt; text-align: center; vertical-align: bottom; background-color: #CCEEFF; white-space: nowrap;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; margin-top: 0pt; margin-left: 9.93pt; text-align: left;">1,951,889</div></td><td style="width: 4.1pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 4.1pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 51.55pt; padding-top: 2.08pt; text-align: center; vertical-align: bottom; background-color: #CCEEFF; white-space: nowrap;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; margin-top: 0pt; margin-left: 12.77pt; text-align: left;">295,638</div></td><td style="width: 4.1pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 4.1pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 50.74pt; padding-top: 2.08pt; text-align: center; vertical-align: bottom; background-color: #CCEEFF; white-space: nowrap;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; margin-top: 0pt; margin-left: 12.37pt; text-align: left;">103,727</div></td><td style="width: 4.1pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 4.1pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 51.68pt; padding-top: 2.08pt; text-align: center; vertical-align: bottom; background-color: #CCEEFF; white-space: nowrap;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; margin-top: 0pt; margin-left: 14.84pt; text-align: left;">40,780</div></td><td style="width: 4.1pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 4.1pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 49.62pt; padding-top: 2.08pt; text-align: center; vertical-align: bottom; background-color: #CCEEFF; white-space: nowrap;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; margin-top: 0pt; margin-left: 20.81pt; text-align: left;">—</div></td><td style="width: 4.1pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 4.1pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 47.34pt; padding-top: 2.08pt; text-align: center; vertical-align: bottom; background-color: #CCEEFF; white-space: nowrap;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; margin-top: 0pt; margin-left: 7.67pt; text-align: left;">2,392,034</div></td></tr><tr class="BRDSX_boxspacer"><td style="height: 3.25pt; width: 96pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 4.1pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 4.1pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 51.87pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 4.1pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 4.1pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 51.55pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 4.1pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 4.1pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 50.74pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 4.1pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 4.1pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 51.68pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 4.1pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 4.1pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 49.62pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 4.1pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 4.1pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 47.34pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td></tr></table><table border="0" cellpadding="0" style="margin-top: 3pt; margin-left: 0pt; border-spacing: 0px;"><tr><td style="width: 20pt; text-align: left; vertical-align: top;"><div style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt;">4.<br/></div></td><td style="vertical-align: top;"><div style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; text-align: justify;">Assumes $100 was invested in the Company for the period starting December 31, 2022, through the end of the listed year. Historical stock performance is not necessarily indicative of future stock performance. </div></td></tr></table> 4738494 10636158 1888753 2948461 266.25 -20370000 1752802 1063510 861316 611437 64.38 31869000 2611138 519365 1127080 528064 96.88 -569000 <table border="0" cellpadding="0" style="margin-top: 3pt; margin-left: 0pt; border-spacing: 0px;"><tr><td style="width: 20pt; text-align: left; vertical-align: top;"><div style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt;">1.<br/></div></td><td style="vertical-align: top;"><div style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; text-align: justify;">Sean A. McCarthy, D. Phil. was our PEO for each year presented. The individuals comprising the Non-PEO NEOs for each year presented are listed below. </div></td></tr></table><table cellpadding="0" class="BRDSX_txttab" style="width: 448pt; margin-left: 20pt; border-spacing: 0px;"><tr class="BRDSX_boxspacer"><td style="height: 6pt; width: 141.34pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 6pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 6pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 141.33pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 6pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 6pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 141.33pt;"><div style="font-size: 1pt;"> </div></td></tr><tr class="BRDSX_header"><td style="width: 141.34pt; padding-bottom: 2.38pt; text-align: left; vertical-align: bottom; border-bottom: 1pt solid #000000;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">2023</div></td><td style="width: 6pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 6pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 141.33pt; padding-bottom: 2.38pt; text-align: left; vertical-align: bottom; border-bottom: 1pt solid #000000;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">2024</div></td><td style="width: 6pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 6pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 141.33pt; padding-bottom: 2.38pt; text-align: left; vertical-align: bottom; border-bottom: 1pt solid #000000;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">2025 </div></td></tr><tr><td style="width: 141.34pt; padding-top: 2.08pt; padding-bottom: 1.63pt; text-align: left; vertical-align: top;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; margin-top: 0pt; text-align: center;">Jeff Landau</div></td><td style="width: 6pt;"><div style="font-size: 1pt;"> </div></td><td style="width: 6pt;"><div style="font-size: 1pt;"> </div></td><td style="width: 141.33pt; padding-top: 2.08pt; padding-bottom: 1.63pt; text-align: left; vertical-align: bottom;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; margin-top: 0pt; text-align: center;">Chris Ogden</div></td><td style="width: 6pt;"><div style="font-size: 1pt;"> </div></td><td style="width: 6pt;"><div style="font-size: 1pt;"> </div></td><td style="width: 141.33pt; padding-top: 2.08pt; padding-bottom: 1.63pt; text-align: left; vertical-align: bottom;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; margin-top: 0pt; text-align: center;">Chris Ogden </div></td></tr><tr><td style="width: 141.34pt; padding-top: 1.33pt; text-align: left; vertical-align: top;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; margin-top: 0pt; text-align: center;">Marcia P. Belvin</div></td><td style="width: 6pt;"><div style="font-size: 1pt;"> </div></td><td style="width: 6pt;"><div style="font-size: 1pt;"> </div></td><td style="width: 141.33pt; padding-top: 1.33pt; text-align: left; vertical-align: bottom;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; margin-top: 0pt; text-align: center;">Wayne Chu</div></td><td style="width: 6pt;"><div style="font-size: 1pt;"> </div></td><td style="width: 6pt;"><div style="font-size: 1pt;"> </div></td><td style="width: 141.33pt; padding-top: 1.33pt; text-align: left; vertical-align: bottom;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; margin-top: 0pt; text-align: center;">Rachael Lester</div></td></tr><tr class="BRDSX_boxspacer"><td style="height: 3.25pt; width: 141.34pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 6pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 6pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 141.33pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 6pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 6pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 141.33pt;"><div style="font-size: 1pt;"> </div></td></tr></table> Sean A. McCarthy, D. Phil. Sean A. McCarthy, D. Phil. Sean A. McCarthy, D. Phil. <table border="0" cellpadding="0" style="margin-top: 3pt; margin-left: 0pt; border-spacing: 0px;"><tr><td style="width: 20pt; text-align: left; vertical-align: top;"><div style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt;">3.<br/></div></td><td style="vertical-align: top;"><div style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; text-align: justify;">Compensation Actually Paid reflects the exclusions and inclusions of certain amounts for the PEO and the Non-PEO NEOs as set forth below. Equity values are calculated in accordance with FASB ASC Topic 718. Amounts in the Exclusion of Stock Awards and Option Awards column are the totals from the Stock Awards and Option Awards columns set forth in the Summary Compensation Table. </div></td></tr></table><table cellpadding="0" class="BRDSX_fintab" style="width: 448pt; margin-left: 20pt; border-spacing: 0px;"><tr class="BRDSX_boxspacer"><td style="height: 6pt; width: 216pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 4.78pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 4.78pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 50.38pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 4.78pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 4.78pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 46.73pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 4.78pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 4.78pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 47.34pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 4.78pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 4.78pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 49.32pt;"><div style="font-size: 1pt;"> </div></td></tr><tr class="BRDSX_header"><td style="width: 216pt; padding-bottom: 2.38pt; text-align: left; vertical-align: bottom; border-bottom: 1pt solid #000000;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; margin-left: 0pt; text-align: left;">Year</div></td><td style="width: 4.78pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 4.78pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 50.38pt; padding-bottom: 2.38pt; text-align: left; vertical-align: bottom; border-bottom: 1pt solid #000000;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Average <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Summary <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Compensation <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Table Total for <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Non-PEO <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">NEOs <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">($)</div></td><td style="width: 4.78pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 4.78pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 46.73pt; padding-bottom: 2.38pt; text-align: left; vertical-align: bottom; border-bottom: 1pt solid #000000;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Average <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Exclusion of <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Stock Awards <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">and Option <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Awards for <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Non-PEO <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">NEOs<br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">($)</div></td><td style="width: 4.78pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 4.78pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 47.34pt; padding-bottom: 2.38pt; text-align: left; vertical-align: bottom; border-bottom: 1pt solid #000000;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Average <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Inclusion of <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Equity Values <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">for Non-PEO <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">NEOs <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">($)</div></td><td style="width: 4.78pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 4.78pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 49.32pt; padding-bottom: 2.38pt; text-align: left; vertical-align: bottom; border-bottom: 1pt solid #000000;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Average <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Compensation <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Actually Paid <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">to Non-PEO <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">NEOs <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">($) </div></td></tr><tr><td style="width: 216pt; padding-top: 2.08pt; text-align: left; vertical-align: bottom; background-color: #CCEEFF;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; margin-top: 0pt; margin-left: 0pt; text-align: left;">2025</div></td><td style="width: 4.78pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 4.78pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 50.38pt; padding-top: 2.08pt; text-align: center; vertical-align: bottom; background-color: #CCEEFF; white-space: nowrap;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; margin-top: 0pt; margin-left: 9.19pt; text-align: left;">1,888,753</div></td><td style="width: 4.78pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 4.78pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 46.73pt; padding-top: 2.08pt; text-align: center; vertical-align: bottom; background-color: #CCEEFF; white-space: nowrap;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; margin-top: 0pt; margin-left: 6.03pt; text-align: left;">(1,332,326)</div></td><td style="width: 4.78pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 4.78pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 47.34pt; padding-top: 2.08pt; text-align: center; vertical-align: bottom; background-color: #CCEEFF; white-space: nowrap;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; margin-top: 0pt; margin-left: 7.67pt; text-align: left;">2,392,034</div></td><td style="width: 4.78pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 4.78pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 49.32pt; padding-top: 2.08pt; text-align: center; vertical-align: bottom; background-color: #CCEEFF; white-space: nowrap;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; margin-top: 0pt; margin-left: 8.66pt; text-align: left;">2,948,461</div></td></tr><tr class="BRDSX_boxspacer"><td style="height: 3.25pt; width: 216pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 4.78pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 4.78pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 50.38pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 4.78pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 4.78pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 46.73pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 4.78pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 4.78pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 47.34pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 4.78pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 4.78pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 49.32pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td></tr></table><div class="BRDSX_ftnote" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; margin-top: 5.25pt; margin-left: 20pt; text-align: left;">The amounts in the Inclusion of Equity Values in the tables above are derived from the amounts set forth in the following tables: </div><table cellpadding="0" class="BRDSX_fintab" style="width: 448pt; margin-left: 20pt; border-spacing: 0px;"><tr class="BRDSX_boxspacer"><td style="height: 6pt; width: 96pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 4.1pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 4.1pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 51.87pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 4.1pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 4.1pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 51.55pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 4.1pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 4.1pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 50.74pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 4.1pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 4.1pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 51.68pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 4.1pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 4.1pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 49.62pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 4.1pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 4.1pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 47.34pt;"><div style="font-size: 1pt;"> </div></td></tr><tr class="BRDSX_header"><td style="width: 96pt; padding-bottom: 2.38pt; text-align: left; vertical-align: bottom; border-bottom: 1pt solid #000000;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; margin-left: 0pt; text-align: left;">Year</div></td><td style="width: 4.1pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 4.1pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 51.87pt; padding-bottom: 2.38pt; text-align: left; vertical-align: bottom; border-bottom: 1pt solid #000000;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Average Year-<br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">End Fair Value <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">of Equity <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Awards <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Granted <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">During Year <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">That <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Remained <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Unvested as of <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Last Day of <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Year for Non-<br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">PEO NEOs <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">($)</div></td><td style="width: 4.1pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 4.1pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 51.55pt; padding-bottom: 2.38pt; text-align: left; vertical-align: bottom; border-bottom: 1pt solid #000000;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Average <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Change in Fair <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Value from <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Last Day of <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Prior Year to <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Last Day of <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Year of <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Unvested <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Equity Awards <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">for Non-PEO <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">NEOs <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">($)</div></td><td style="width: 4.1pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 4.1pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 50.74pt; padding-bottom: 2.38pt; text-align: left; vertical-align: bottom; border-bottom: 1pt solid #000000;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Average <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Vesting-Date <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Fair Value of <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Equity Awards <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Granted <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">During Year <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">that Vested <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">During Year <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">for Non-PEO <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">NEOs <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">($)</div></td><td style="width: 4.1pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 4.1pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 51.68pt; padding-bottom: 2.38pt; text-align: left; vertical-align: bottom; border-bottom: 1pt solid #000000;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Average <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Change in Fair <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Value from <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Last Day of <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Prior Year to <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Vesting Date of <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Unvested <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Equity Awards <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">that Vested <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">During Year <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">for Non-PEO <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">NEOs <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">($)</div></td><td style="width: 4.1pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 4.1pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 49.62pt; padding-bottom: 2.38pt; text-align: left; vertical-align: bottom; border-bottom: 1pt solid #000000;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Average Fair <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Value at Last <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Day of Prior <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Year of Equity <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Awards <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Forfeited <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">During Year <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">for Non-PEO <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">NEOs <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">($)</div></td><td style="width: 4.1pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 4.1pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 47.34pt; padding-bottom: 2.38pt; text-align: left; vertical-align: bottom; border-bottom: 1pt solid #000000;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Total - <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Average <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Inclusion of<br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Equity Values <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">for Non-PEO <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">NEOs<br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">($) </div></td></tr><tr><td style="width: 96pt; padding-top: 2.08pt; text-align: left; vertical-align: bottom; background-color: #CCEEFF;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; margin-top: 0pt; margin-left: 0pt; text-align: left;">2025</div></td><td style="width: 4.1pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 4.1pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 51.87pt; padding-top: 2.08pt; text-align: center; vertical-align: bottom; background-color: #CCEEFF; white-space: nowrap;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; margin-top: 0pt; margin-left: 9.93pt; text-align: left;">1,951,889</div></td><td style="width: 4.1pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 4.1pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 51.55pt; padding-top: 2.08pt; text-align: center; vertical-align: bottom; background-color: #CCEEFF; white-space: nowrap;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; margin-top: 0pt; margin-left: 12.77pt; text-align: left;">295,638</div></td><td style="width: 4.1pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 4.1pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 50.74pt; padding-top: 2.08pt; text-align: center; vertical-align: bottom; background-color: #CCEEFF; white-space: nowrap;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; margin-top: 0pt; margin-left: 12.37pt; text-align: left;">103,727</div></td><td style="width: 4.1pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 4.1pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 51.68pt; padding-top: 2.08pt; text-align: center; vertical-align: bottom; background-color: #CCEEFF; white-space: nowrap;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; margin-top: 0pt; margin-left: 14.84pt; text-align: left;">40,780</div></td><td style="width: 4.1pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 4.1pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 49.62pt; padding-top: 2.08pt; text-align: center; vertical-align: bottom; background-color: #CCEEFF; white-space: nowrap;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; margin-top: 0pt; margin-left: 20.81pt; text-align: left;">—</div></td><td style="width: 4.1pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 4.1pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 47.34pt; padding-top: 2.08pt; text-align: center; vertical-align: bottom; background-color: #CCEEFF; white-space: nowrap;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; margin-top: 0pt; margin-left: 7.67pt; text-align: left;">2,392,034</div></td></tr><tr class="BRDSX_boxspacer"><td style="height: 3.25pt; width: 96pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 4.1pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 4.1pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 51.87pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 4.1pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 4.1pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 51.55pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 4.1pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 4.1pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 50.74pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 4.1pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 4.1pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 51.68pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 4.1pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 4.1pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 49.62pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 4.1pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 4.1pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 47.34pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td></tr></table> <table border="0" cellpadding="0" style="margin-top: 3pt; margin-left: 0pt; border-spacing: 0px;"><tr><td style="width: 20pt; text-align: left; vertical-align: top;"><div style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt;">3.<br/></div></td><td style="vertical-align: top;"><div style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; text-align: justify;">Compensation Actually Paid reflects the exclusions and inclusions of certain amounts for the PEO and the Non-PEO NEOs as set forth below. Equity values are calculated in accordance with FASB ASC Topic 718. Amounts in the Exclusion of Stock Awards and Option Awards column are the totals from the Stock Awards and Option Awards columns set forth in the Summary Compensation Table. </div></td></tr></table><table cellpadding="0" class="BRDSX_fintab" style="margin-top: 4pt; width: 448pt; margin-left: 20pt; border-spacing: 0px;"><tr class="BRDSX_boxspacer"><td style="height: 6pt; width: 216pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 4.76pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 4.76pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 50.38pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 4.76pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 4.76pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 46.87pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 4.76pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 4.76pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 47.34pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 4.76pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 4.76pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 49.32pt;"><div style="font-size: 1pt;"> </div></td></tr><tr class="BRDSX_header"><td style="width: 216pt; padding-bottom: 2.38pt; text-align: left; vertical-align: bottom; border-bottom: 1pt solid #000000;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; margin-left: 0pt; text-align: left;">Year</div></td><td style="width: 4.76pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 4.76pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 50.38pt; padding-bottom: 2.38pt; text-align: left; vertical-align: bottom; border-bottom: 1pt solid #000000;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Summary <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Compensation <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Table Total for <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Sean <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">A. McCarthy, <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">D. Phil. <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">($)</div></td><td style="width: 4.76pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 4.76pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 46.87pt; padding-bottom: 2.38pt; text-align: left; vertical-align: bottom; border-bottom: 1pt solid #000000;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Exclusion of <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Stock Awards <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">and Option <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Awards for <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Sean <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">A. McCarthy, <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">D. Phil. <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">($)</div></td><td style="width: 4.76pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 4.76pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 47.34pt; padding-bottom: 2.38pt; text-align: left; vertical-align: bottom; border-bottom: 1pt solid #000000;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Inclusion of <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Equity Values <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">for Sean <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">A. McCarthy, <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">D. Phil. <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">($)</div></td><td style="width: 4.76pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 4.76pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 49.32pt; padding-bottom: 2.38pt; text-align: left; vertical-align: bottom; border-bottom: 1pt solid #000000;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Compensation <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Actually Paid <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">to Sean <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">A. McCarthy, <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">D. Phil. <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">($) </div></td></tr><tr><td style="width: 216pt; padding-top: 2.08pt; text-align: left; vertical-align: bottom; background-color: #CCEEFF;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; margin-top: 0pt; margin-left: 0pt; text-align: left;">2025</div></td><td style="width: 4.76pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 4.76pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 50.38pt; padding-top: 2.08pt; text-align: center; vertical-align: bottom; background-color: #CCEEFF; white-space: nowrap;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; margin-top: 0pt; margin-left: 9.19pt; text-align: left;">4,738,494</div></td><td style="width: 4.76pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 4.76pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 46.87pt; padding-top: 2.08pt; text-align: center; vertical-align: bottom; background-color: #CCEEFF; white-space: nowrap;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; margin-top: 0pt; margin-left: 6.11pt; text-align: left;">(3,308,633)</div></td><td style="width: 4.76pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 4.76pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 47.34pt; padding-top: 2.08pt; text-align: center; vertical-align: bottom; background-color: #CCEEFF; white-space: nowrap;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; margin-top: 0pt; margin-left: 7.68pt; text-align: left;">9,206,297</div></td><td style="width: 4.76pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 4.76pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 49.32pt; padding-top: 2.08pt; text-align: center; vertical-align: bottom; background-color: #CCEEFF; white-space: nowrap;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; margin-top: 0pt; margin-left: 6.66pt; text-align: left;">10,636,158</div></td></tr><tr class="BRDSX_boxspacer"><td style="height: 3.25pt; width: 216pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 4.76pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 4.76pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 50.38pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 4.76pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 4.76pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 46.87pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 4.76pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 4.76pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 47.34pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 4.76pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 4.76pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 49.32pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td></tr></table><div class="BRDSX_ftnote" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; margin-top: 5.25pt; margin-left: 20pt; text-align: left;">The amounts in the Inclusion of Equity Values in the tables above are derived from the amounts set forth in the following tables: </div><table cellpadding="0" class="BRDSX_fintab" style="width: 448pt; margin-left: 20pt; border-spacing: 0px;"><tr class="BRDSX_boxspacer"><td style="height: 6pt; width: 120pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 3.79pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 3.79pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 46.87pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 3.79pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 3.79pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 46.87pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 3.79pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 3.79pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 46.87pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 3.79pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 3.79pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 46.87pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 3.79pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 3.79pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 48.2pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 3.79pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 3.79pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 46.87pt;"><div style="font-size: 1pt;"> </div></td></tr><tr class="BRDSX_header"><td style="width: 120pt; padding-bottom: 2.38pt; text-align: left; vertical-align: bottom; border-bottom: 1pt solid #000000;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; margin-left: 0pt; text-align: left;">Year</div></td><td style="width: 3.79pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 3.79pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 46.87pt; padding-bottom: 2.38pt; text-align: left; vertical-align: bottom; border-bottom: 1pt solid #000000;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Year-End <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Fair Value of <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Equity <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Awards <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Granted <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">During Year <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">That <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Remained <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Unvested as <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">of Last Day <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">of Year for <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Sean <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">A. McCarthy, <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">D. Phil. <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">($)</div></td><td style="width: 3.79pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 3.79pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 46.87pt; padding-bottom: 2.38pt; text-align: left; vertical-align: bottom; border-bottom: 1pt solid #000000;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Change in <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Fair Value <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">from Last <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Day of Prior <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Year to Last <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Day of Year <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">of Unvested <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Equity <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Awards for <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Sean <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">A. McCarthy, <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">D. Phil. <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">($)</div></td><td style="width: 3.79pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 3.79pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 46.87pt; padding-bottom: 2.38pt; text-align: left; vertical-align: bottom; border-bottom: 1pt solid #000000;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Vesting-Date <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Fair Value of <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Equity <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Awards <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Granted <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">During Year <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">that Vested <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">During Year <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">for Sean <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">A. McCarthy, <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">D. Phil. <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">($)</div></td><td style="width: 3.79pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 3.79pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 46.87pt; padding-bottom: 2.38pt; text-align: left; vertical-align: bottom; border-bottom: 1pt solid #000000;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Change in <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Fair Value <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">from Last <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Day of Prior <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Year to <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Vesting Date <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">of Unvested <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Equity <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Awards that <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Vested <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">During Year <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">for Sean <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">A. McCarthy, <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">D. Phil. <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">($)</div></td><td style="width: 3.79pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 3.79pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 48.2pt; padding-bottom: 2.38pt; text-align: left; vertical-align: bottom; border-bottom: 1pt solid #000000;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Fair Value <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">at Last Day of <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Prior Year <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">of Equity <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Awards <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Forfeited <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">During Year <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">for Sean <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">A. McCarthy, <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">D. Phil. <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">($)</div></td><td style="width: 3.79pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 3.79pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 46.87pt; padding-bottom: 2.38pt; text-align: left; vertical-align: bottom; border-bottom: 1pt solid #000000;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Total - <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Inclusion of<br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Equity <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Values for <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Sean <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">A. McCarthy, <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">D. Phil. <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">($) </div></td></tr><tr><td style="width: 120pt; padding-top: 2.08pt; text-align: left; vertical-align: bottom; background-color: #CCEEFF;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; margin-top: 0pt; margin-left: 0pt; text-align: left;">2025</div></td><td style="width: 3.79pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 3.79pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 46.87pt; padding-top: 2.08pt; text-align: center; vertical-align: bottom; background-color: #CCEEFF; white-space: nowrap;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; margin-top: 0pt; margin-left: 7.43pt; text-align: left;">6,876,499 </div></td><td style="width: 3.79pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 3.79pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 46.87pt; padding-top: 2.08pt; text-align: center; vertical-align: bottom; background-color: #CCEEFF; white-space: nowrap;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; margin-top: 0pt; margin-left: 7.43pt; text-align: left;">1,302,775 </div></td><td style="width: 3.79pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 3.79pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 46.87pt; padding-top: 2.08pt; text-align: center; vertical-align: bottom; background-color: #CCEEFF; white-space: nowrap;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; margin-top: 0pt; margin-left: 10.44pt; text-align: left;">780,454 </div></td><td style="width: 3.79pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 3.79pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 46.87pt; padding-top: 2.08pt; text-align: center; vertical-align: bottom; background-color: #CCEEFF; white-space: nowrap;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; margin-top: 0pt; margin-left: 10.44pt; text-align: left;">246,569 </div></td><td style="width: 3.79pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 3.79pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 48.2pt; padding-top: 2.08pt; text-align: center; vertical-align: bottom; background-color: #CCEEFF; white-space: nowrap;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; margin-top: 0pt; margin-left: 20.1pt; text-align: left;">—</div></td><td style="width: 3.79pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 3.79pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 46.87pt; padding-top: 2.08pt; text-align: center; vertical-align: bottom; background-color: #CCEEFF; white-space: nowrap;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; margin-top: 0pt; margin-left: 7.45pt; text-align: left;">9,206,297</div></td></tr><tr class="BRDSX_boxspacer"><td style="height: 3.25pt; width: 120pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 3.79pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 3.79pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 46.87pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 3.79pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 3.79pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 46.87pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 3.79pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 3.79pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 46.87pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 3.79pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 3.79pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 46.87pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 3.79pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 3.79pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 48.2pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 3.79pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 3.79pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 46.87pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td></tr></table> 4738494 -3308633 9206297 10636158 1888753 -1332326 2392034 2948461 <div class="BRDSX_ftnote" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; margin-top: 5.25pt; margin-left: 20pt; text-align: left;">The amounts in the Inclusion of Equity Values in the tables above are derived from the amounts set forth in the following tables: </div><table cellpadding="0" class="BRDSX_fintab" style="width: 448pt; margin-left: 20pt; border-spacing: 0px;"><tr class="BRDSX_boxspacer"><td style="height: 6pt; width: 120pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 3.79pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 3.79pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 46.87pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 3.79pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 3.79pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 46.87pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 3.79pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 3.79pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 46.87pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 3.79pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 3.79pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 46.87pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 3.79pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 3.79pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 48.2pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 3.79pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 3.79pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 46.87pt;"><div style="font-size: 1pt;"> </div></td></tr><tr class="BRDSX_header"><td style="width: 120pt; padding-bottom: 2.38pt; text-align: left; vertical-align: bottom; border-bottom: 1pt solid #000000;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; margin-left: 0pt; text-align: left;">Year</div></td><td style="width: 3.79pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 3.79pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 46.87pt; padding-bottom: 2.38pt; text-align: left; vertical-align: bottom; border-bottom: 1pt solid #000000;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Year-End <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Fair Value of <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Equity <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Awards <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Granted <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">During Year <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">That <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Remained <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Unvested as <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">of Last Day <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">of Year for <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Sean <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">A. McCarthy, <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">D. Phil. <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">($)</div></td><td style="width: 3.79pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 3.79pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 46.87pt; padding-bottom: 2.38pt; text-align: left; vertical-align: bottom; border-bottom: 1pt solid #000000;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Change in <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Fair Value <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">from Last <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Day of Prior <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Year to Last <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Day of Year <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">of Unvested <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Equity <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Awards for <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Sean <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">A. McCarthy, <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">D. Phil. <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">($)</div></td><td style="width: 3.79pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 3.79pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 46.87pt; padding-bottom: 2.38pt; text-align: left; vertical-align: bottom; border-bottom: 1pt solid #000000;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Vesting-Date <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Fair Value of <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Equity <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Awards <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Granted <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">During Year <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">that Vested <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">During Year <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">for Sean <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">A. McCarthy, <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">D. Phil. <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">($)</div></td><td style="width: 3.79pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 3.79pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 46.87pt; padding-bottom: 2.38pt; text-align: left; vertical-align: bottom; border-bottom: 1pt solid #000000;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Change in <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Fair Value <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">from Last <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Day of Prior <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Year to <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Vesting Date <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">of Unvested <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Equity <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Awards that <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Vested <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">During Year <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">for Sean <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">A. McCarthy, <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">D. Phil. <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">($)</div></td><td style="width: 3.79pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 3.79pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 48.2pt; padding-bottom: 2.38pt; text-align: left; vertical-align: bottom; border-bottom: 1pt solid #000000;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Fair Value <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">at Last Day of <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Prior Year <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">of Equity <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Awards <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Forfeited <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">During Year <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">for Sean <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">A. McCarthy, <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">D. Phil. <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">($)</div></td><td style="width: 3.79pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 3.79pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 46.87pt; padding-bottom: 2.38pt; text-align: left; vertical-align: bottom; border-bottom: 1pt solid #000000;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Total - <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Inclusion of<br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Equity <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Values for <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Sean <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">A. McCarthy, <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">D. Phil. <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">($) </div></td></tr><tr><td style="width: 120pt; padding-top: 2.08pt; text-align: left; vertical-align: bottom; background-color: #CCEEFF;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; margin-top: 0pt; margin-left: 0pt; text-align: left;">2025</div></td><td style="width: 3.79pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 3.79pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 46.87pt; padding-top: 2.08pt; text-align: center; vertical-align: bottom; background-color: #CCEEFF; white-space: nowrap;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; margin-top: 0pt; margin-left: 7.43pt; text-align: left;">6,876,499 </div></td><td style="width: 3.79pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 3.79pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 46.87pt; padding-top: 2.08pt; text-align: center; vertical-align: bottom; background-color: #CCEEFF; white-space: nowrap;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; margin-top: 0pt; margin-left: 7.43pt; text-align: left;">1,302,775 </div></td><td style="width: 3.79pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 3.79pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 46.87pt; padding-top: 2.08pt; text-align: center; vertical-align: bottom; background-color: #CCEEFF; white-space: nowrap;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; margin-top: 0pt; margin-left: 10.44pt; text-align: left;">780,454 </div></td><td style="width: 3.79pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 3.79pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 46.87pt; padding-top: 2.08pt; text-align: center; vertical-align: bottom; background-color: #CCEEFF; white-space: nowrap;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; margin-top: 0pt; margin-left: 10.44pt; text-align: left;">246,569 </div></td><td style="width: 3.79pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 3.79pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 48.2pt; padding-top: 2.08pt; text-align: center; vertical-align: bottom; background-color: #CCEEFF; white-space: nowrap;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; margin-top: 0pt; margin-left: 20.1pt; text-align: left;">—</div></td><td style="width: 3.79pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 3.79pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 46.87pt; padding-top: 2.08pt; text-align: center; vertical-align: bottom; background-color: #CCEEFF; white-space: nowrap;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; margin-top: 0pt; margin-left: 7.45pt; text-align: left;">9,206,297</div></td></tr><tr class="BRDSX_boxspacer"><td style="height: 3.25pt; width: 120pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 3.79pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 3.79pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 46.87pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 3.79pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 3.79pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 46.87pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 3.79pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 3.79pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 46.87pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 3.79pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 3.79pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 46.87pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 3.79pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 3.79pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 48.2pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 3.79pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 3.79pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 46.87pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td></tr></table><table cellpadding="0" class="BRDSX_fintab" style="width: 448pt; margin-left: 20pt; border-spacing: 0px;"><tr class="BRDSX_boxspacer"><td style="height: 6pt; width: 96pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 4.1pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 4.1pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 51.87pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 4.1pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 4.1pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 51.55pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 4.1pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 4.1pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 50.74pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 4.1pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 4.1pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 51.68pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 4.1pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 4.1pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 49.62pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 4.1pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 4.1pt;"><div style="font-size: 1pt;"> </div></td><td style="height: 6pt; width: 47.34pt;"><div style="font-size: 1pt;"> </div></td></tr><tr class="BRDSX_header"><td style="width: 96pt; padding-bottom: 2.38pt; text-align: left; vertical-align: bottom; border-bottom: 1pt solid #000000;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; margin-left: 0pt; text-align: left;">Year</div></td><td style="width: 4.1pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 4.1pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 51.87pt; padding-bottom: 2.38pt; text-align: left; vertical-align: bottom; border-bottom: 1pt solid #000000;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Average Year-<br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">End Fair Value <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">of Equity <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Awards <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Granted <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">During Year <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">That <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Remained <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Unvested as of <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Last Day of <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Year for Non-<br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">PEO NEOs <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">($)</div></td><td style="width: 4.1pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 4.1pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 51.55pt; padding-bottom: 2.38pt; text-align: left; vertical-align: bottom; border-bottom: 1pt solid #000000;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Average <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Change in Fair <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Value from <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Last Day of <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Prior Year to <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Last Day of <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Year of <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Unvested <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Equity Awards <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">for Non-PEO <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">NEOs <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">($)</div></td><td style="width: 4.1pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 4.1pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 50.74pt; padding-bottom: 2.38pt; text-align: left; vertical-align: bottom; border-bottom: 1pt solid #000000;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Average <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Vesting-Date <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Fair Value of <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Equity Awards <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Granted <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">During Year <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">that Vested <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">During Year <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">for Non-PEO <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">NEOs <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">($)</div></td><td style="width: 4.1pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 4.1pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 51.68pt; padding-bottom: 2.38pt; text-align: left; vertical-align: bottom; border-bottom: 1pt solid #000000;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Average <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Change in Fair <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Value from <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Last Day of <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Prior Year to <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Vesting Date of <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Unvested <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Equity Awards <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">that Vested <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">During Year <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">for Non-PEO <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">NEOs <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">($)</div></td><td style="width: 4.1pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 4.1pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 49.62pt; padding-bottom: 2.38pt; text-align: left; vertical-align: bottom; border-bottom: 1pt solid #000000;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Average Fair <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Value at Last <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Day of Prior <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Year of Equity <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Awards <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Forfeited <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">During Year <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">for Non-PEO <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">NEOs <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">($)</div></td><td style="width: 4.1pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 4.1pt; border-bottom: none;"><div style="font-size: 1pt;"> </div></td><td style="width: 47.34pt; padding-bottom: 2.38pt; text-align: left; vertical-align: bottom; border-bottom: 1pt solid #000000;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Total - <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Average <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Inclusion of<br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">Equity Values <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">for Non-PEO <br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">NEOs<br/></div><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; font-weight: bold; margin-top: 0pt; text-align: center;">($) </div></td></tr><tr><td style="width: 96pt; padding-top: 2.08pt; text-align: left; vertical-align: bottom; background-color: #CCEEFF;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; margin-top: 0pt; margin-left: 0pt; text-align: left;">2025</div></td><td style="width: 4.1pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 4.1pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 51.87pt; padding-top: 2.08pt; text-align: center; vertical-align: bottom; background-color: #CCEEFF; white-space: nowrap;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; margin-top: 0pt; margin-left: 9.93pt; text-align: left;">1,951,889</div></td><td style="width: 4.1pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 4.1pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 51.55pt; padding-top: 2.08pt; text-align: center; vertical-align: bottom; background-color: #CCEEFF; white-space: nowrap;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; margin-top: 0pt; margin-left: 12.77pt; text-align: left;">295,638</div></td><td style="width: 4.1pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 4.1pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 50.74pt; padding-top: 2.08pt; text-align: center; vertical-align: bottom; background-color: #CCEEFF; white-space: nowrap;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; margin-top: 0pt; margin-left: 12.37pt; text-align: left;">103,727</div></td><td style="width: 4.1pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 4.1pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 51.68pt; padding-top: 2.08pt; text-align: center; vertical-align: bottom; background-color: #CCEEFF; white-space: nowrap;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; margin-top: 0pt; margin-left: 14.84pt; text-align: left;">40,780</div></td><td style="width: 4.1pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 4.1pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 49.62pt; padding-top: 2.08pt; text-align: center; vertical-align: bottom; background-color: #CCEEFF; white-space: nowrap;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; margin-top: 0pt; margin-left: 20.81pt; text-align: left;">—</div></td><td style="width: 4.1pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 4.1pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="width: 47.34pt; padding-top: 2.08pt; text-align: center; vertical-align: bottom; background-color: #CCEEFF; white-space: nowrap;"><div class="BRDSX_fpara" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt; margin-top: 0pt; margin-left: 7.67pt; text-align: left;">2,392,034</div></td></tr><tr class="BRDSX_boxspacer"><td style="height: 3.25pt; width: 96pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 4.1pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 4.1pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 51.87pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 4.1pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 4.1pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 51.55pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 4.1pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 4.1pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 50.74pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 4.1pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 4.1pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 51.68pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 4.1pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 4.1pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 49.62pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 4.1pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 4.1pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td><td style="height: 3.25pt; width: 47.34pt; background-color: #CCEEFF;"><div style="font-size: 1pt;"> </div></td></tr></table> 6876499 1302775 780454 246569 0 9206297 1951889 295638 103727 40780 0 2392034 <div class="BRDSX_h3" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt; font-style: italic; font-weight: bold; margin-top: 6.75pt; margin-left: 0pt; text-align: left;">Relationship Between PEO and Non-PEO NEO Compensation Actually Paid and Company Total Shareholder Return (“TSR”) </div><div class="BRDSX_para" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt; margin-top: 6pt; margin-left: 0pt; text-indent: 20pt; text-align: justify;">The following chart sets forth the relationship between Compensation Actually Paid to our PEO, the average of Compensation Actually Paid to our Non-PEO NEOs, and the Company’s cumulative TSR over the three most recently completed fiscal years. </div><img alt="" src="ny20064651x2_pvpchart01.jpg" style="height: 343px; width: 542px;"/> <div class="BRDSX_h3" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt; font-style: italic; font-weight: bold; margin-top: 14.5pt; margin-left: 0pt; text-align: left;">Relationship Between PEO and Non-PEO NEO Compensation Actually Paid and Net Income </div><div class="BRDSX_para" style="color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt; margin-top: 6pt; margin-left: 0pt; text-indent: 20pt; text-align: justify;">The following chart sets forth the relationship between Compensation Actually Paid to our PEO, the average of Compensation Actually Paid to our Non-PEO NEOs, and our Net Income during the three most recently completed fiscal years.</div><img alt="" src="ny20064651x2_pvpchart02.jpg" style="height: 349px; width: 543px;"/> DEF 14A 0001501989 false